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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX43
All Species:
9.39
Human Site:
S619
Identified Species:
17.22
UniProt:
Q9NXZ2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXZ2
NP_061135.2
648
72844
S619
S
I
P
E
E
L
V
S
M
A
E
R
F
K
A
Chimpanzee
Pan troglodytes
XP_518584
648
72811
S619
S
I
P
E
E
L
V
S
M
A
E
R
F
K
A
Rhesus Macaque
Macaca mulatta
XP_001112413
648
73197
S619
S
I
P
E
E
L
V
S
M
A
E
R
F
K
A
Dog
Lupus familis
XP_853740
646
73189
A617
S
V
P
E
E
L
V
A
M
A
E
R
Y
E
A
Cat
Felis silvestris
Mouse
Mus musculus
XP_001480973
646
72253
L617
N
I
P
E
E
L
V
L
M
A
E
R
Y
K
A
Rat
Rattus norvegicus
XP_001060057
620
69575
L591
N
I
P
E
E
L
V
L
M
A
E
R
Y
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426195
445
49951
V438
I
E
E
Y
V
H
R
V
G
R
T
G
R
A
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P19109
719
78529
N662
E
I
N
P
A
L
E
N
L
A
R
N
S
R
Y
Honey Bee
Apis mellifera
XP_394925
593
68127
N585
R
V
D
K
Y
D
Y
N
R
S
S
R
N
R
R
Nematode Worm
Caenorhab. elegans
NP_496973
504
56752
N497
F
R
N
N
K
N
K
N
S
N
F
Q
A
S
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W4R3
591
64603
S580
D
K
R
S
R
S
T
S
N
F
V
P
H
G
G
Baker's Yeast
Sacchar. cerevisiae
P24783
546
60981
G539
R
Q
R
D
G
G
W
G
N
R
G
R
S
N
Y
Red Bread Mold
Neurospora crassa
Q7SBC6
562
60181
L555
S
V
G
G
A
N
A
L
P
L
N
N
R
R
W
Conservation
Percent
Protein Identity:
100
99
96.7
75.9
N.A.
76.8
74.5
N.A.
N.A.
47.9
N.A.
N.A.
N.A.
29.7
45.3
36.5
N.A.
Protein Similarity:
100
99.6
97.9
87.1
N.A.
86.1
83
N.A.
N.A.
57.4
N.A.
N.A.
N.A.
47.9
62.9
51.2
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
80
80
N.A.
N.A.
0
N.A.
N.A.
N.A.
20
6.6
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
0
N.A.
N.A.
N.A.
40
40
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.2
36.1
34.2
Protein Similarity:
N.A.
N.A.
N.A.
53.7
54.1
51
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
16
0
8
8
0
54
0
0
8
8
47
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
8
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
8
47
47
0
8
0
0
0
47
0
0
8
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
8
8
0
24
0
0
% F
% Gly:
0
0
8
8
8
8
0
8
8
0
8
8
0
8
16
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
47
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
8
8
0
8
0
0
0
0
0
0
39
0
% K
% Leu:
0
0
0
0
0
54
0
24
8
8
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
47
0
0
0
0
0
0
% M
% Asn:
16
0
16
8
0
16
0
24
16
8
8
16
8
8
0
% N
% Pro:
0
0
47
8
0
0
0
0
8
0
0
8
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
16
8
16
0
8
0
8
0
8
16
8
62
16
24
8
% R
% Ser:
39
0
0
8
0
8
0
31
8
8
8
0
16
8
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% T
% Val:
0
24
0
0
8
0
47
8
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
8
8
0
8
0
0
0
0
0
24
0
24
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _