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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP4R2
All Species:
12.73
Human Site:
S199
Identified Species:
25.45
UniProt:
Q9NY27
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NY27
NP_777567.1
417
46898
S199
G
L
P
E
S
T
D
S
K
E
A
N
L
Q
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089385
114
12679
Dog
Lupus familis
XP_533762
414
46506
S199
G
L
P
E
S
T
D
S
K
E
S
N
L
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q0VGB7
417
46460
S199
G
L
P
E
S
T
D
S
K
D
S
E
L
Q
L
Rat
Rattus norvegicus
NP_001100083
413
45910
S199
G
L
P
E
S
T
D
S
R
D
S
D
L
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521306
173
19445
Chicken
Gallus gallus
Q5ZMU6
405
44944
H199
G
L
P
D
S
T
E
H
K
E
S
S
L
Q
Q
Frog
Xenopus laevis
Q5M7D6
403
44536
N199
G
L
P
D
S
T
E
N
K
E
S
D
L
Q
Q
Zebra Danio
Brachydanio rerio
Q6P964
420
46175
K199
L
P
D
S
T
E
S
K
E
Q
A
S
E
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W2U4
609
66790
D204
A
S
C
P
R
S
D
D
N
D
Q
P
K
A
K
Honey Bee
Apis mellifera
XP_001122932
568
63871
V200
T
P
L
L
H
T
V
V
P
T
N
T
V
V
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783289
597
63190
R206
D
A
M
N
G
V
S
R
P
Y
Y
N
S
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
26.6
94.4
N.A.
82.7
80.5
N.A.
36.6
77.4
61.3
49.7
N.A.
26.4
26.4
N.A.
26.8
Protein Similarity:
100
N.A.
26.8
97.3
N.A.
89.6
88.9
N.A.
39.3
86.8
76
64.7
N.A.
43.1
44.8
N.A.
43
P-Site Identity:
100
N.A.
0
93.3
N.A.
73.3
66.6
N.A.
0
66.6
66.6
13.3
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
0
100
N.A.
86.6
93.3
N.A.
0
93.3
100
40
N.A.
26.6
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
0
0
0
0
0
0
17
0
0
9
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
17
0
0
42
9
0
25
0
17
0
9
0
% D
% Glu:
0
0
0
34
0
9
17
0
9
34
0
9
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
50
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
9
42
0
0
0
9
0
17
% K
% Leu:
9
50
9
9
0
0
0
0
0
0
0
0
50
0
17
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
9
9
0
9
25
0
0
0
% N
% Pro:
0
17
50
9
0
0
0
0
17
0
0
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
9
0
0
59
34
% Q
% Arg:
0
0
0
0
9
0
0
9
9
0
0
0
0
0
0
% R
% Ser:
0
9
0
9
50
9
17
34
0
0
42
17
9
0
9
% S
% Thr:
9
0
0
0
9
59
0
0
0
9
0
9
0
0
9
% T
% Val:
0
0
0
0
0
9
9
9
0
0
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _