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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP4R2
All Species:
10
Human Site:
S216
Identified Species:
20
UniProt:
Q9NY27
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NY27
NP_777567.1
417
46898
S216
E
K
N
H
S
D
S
S
T
S
E
S
E
V
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089385
114
12679
Dog
Lupus familis
XP_533762
414
46506
A216
D
K
S
H
S
D
S
A
T
S
E
S
E
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q0VGB7
417
46460
S216
E
K
G
H
S
D
S
S
A
S
E
S
E
V
S
Rat
Rattus norvegicus
NP_001100083
413
45910
S216
E
K
G
H
S
D
S
S
A
S
D
S
E
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521306
173
19445
Chicken
Gallus gallus
Q5ZMU6
405
44944
P216
D
K
K
H
S
D
S
P
A
S
D
S
E
G
A
Frog
Xenopus laevis
Q5M7D6
403
44536
V216
K
S
Q
S
D
S
A
V
S
D
D
G
S
Q
A
Zebra Danio
Brachydanio rerio
Q6P964
420
46175
S216
T
V
N
E
S
S
A
S
E
A
E
S
H
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W2U4
609
66790
E221
K
L
E
I
D
G
E
E
R
S
E
A
S
D
E
Honey Bee
Apis mellifera
XP_001122932
568
63871
H217
F
D
T
E
E
L
S
H
E
K
V
E
S
T
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783289
597
63190
P223
A
P
L
Q
F
A
Y
P
L
G
Q
S
M
T
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
26.6
94.4
N.A.
82.7
80.5
N.A.
36.6
77.4
61.3
49.7
N.A.
26.4
26.4
N.A.
26.8
Protein Similarity:
100
N.A.
26.8
97.3
N.A.
89.6
88.9
N.A.
39.3
86.8
76
64.7
N.A.
43.1
44.8
N.A.
43
P-Site Identity:
100
N.A.
0
73.3
N.A.
86.6
80
N.A.
0
53.3
0
33.3
N.A.
13.3
13.3
N.A.
13.3
P-Site Similarity:
100
N.A.
0
93.3
N.A.
86.6
86.6
N.A.
0
73.3
33.3
46.6
N.A.
26.6
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
9
17
9
25
9
0
9
0
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
9
0
0
17
42
0
0
0
9
25
0
0
9
0
% D
% Glu:
25
0
9
17
9
0
9
9
17
0
42
9
42
0
9
% E
% Phe:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
17
0
0
9
0
0
0
9
0
9
0
17
9
% G
% His:
0
0
0
42
0
0
0
9
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
17
42
9
0
0
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
0
9
9
0
0
9
0
0
9
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
0
0
0
0
0
17
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
9
0
0
0
0
0
0
9
0
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
0
9
9
9
50
17
50
34
9
50
0
59
25
9
50
% S
% Thr:
9
0
9
0
0
0
0
0
17
0
0
0
0
17
0
% T
% Val:
0
9
0
0
0
0
0
9
0
0
9
0
0
25
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _