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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP4R2
All Species:
17.27
Human Site:
T391
Identified Species:
34.55
UniProt:
Q9NY27
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NY27
NP_777567.1
417
46898
T391
V
G
S
N
S
S
K
T
G
E
I
L
S
E
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089385
114
12679
G89
G
S
N
S
S
K
T
G
E
I
L
S
E
S
S
Dog
Lupus familis
XP_533762
414
46506
T388
L
G
S
N
S
S
K
T
G
E
I
L
S
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q0VGB7
417
46460
T391
G
G
P
P
S
S
K
T
G
E
S
V
S
V
P
Rat
Rattus norvegicus
NP_001100083
413
45910
T388
G
G
P
P
A
R
K
T
G
E
C
V
S
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521306
173
19445
P148
P
K
S
S
L
S
A
P
M
T
T
N
G
L
P
Chicken
Gallus gallus
Q5ZMU6
405
44944
T379
L
G
S
Y
G
S
E
T
P
E
T
S
S
E
T
Frog
Xenopus laevis
Q5M7D6
403
44536
S377
L
A
T
S
S
G
K
S
T
E
T
L
T
L
S
Zebra Danio
Brachydanio rerio
Q6P964
420
46175
A387
S
S
A
E
T
P
S
A
S
P
S
S
S
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W2U4
609
66790
S422
P
A
E
E
K
I
A
S
S
E
S
K
P
K
T
Honey Bee
Apis mellifera
XP_001122932
568
63871
H519
T
S
T
I
N
K
I
H
D
S
D
T
V
I
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783289
597
63190
E523
L
D
R
M
A
A
V
E
S
S
A
D
A
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
26.6
94.4
N.A.
82.7
80.5
N.A.
36.6
77.4
61.3
49.7
N.A.
26.4
26.4
N.A.
26.8
Protein Similarity:
100
N.A.
26.8
97.3
N.A.
89.6
88.9
N.A.
39.3
86.8
76
64.7
N.A.
43.1
44.8
N.A.
43
P-Site Identity:
100
N.A.
13.3
93.3
N.A.
53.3
46.6
N.A.
13.3
46.6
33.3
6.6
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
N.A.
33.3
100
N.A.
60
60
N.A.
20
66.6
66.6
20
N.A.
26.6
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
9
0
17
9
17
9
0
0
9
0
9
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
9
0
9
9
0
0
0
% D
% Glu:
0
0
9
17
0
0
9
9
9
59
0
0
9
25
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
25
42
0
0
9
9
0
9
34
0
0
0
9
9
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
9
9
0
0
9
17
0
0
9
0
% I
% Lys:
0
9
0
0
9
17
42
0
0
0
0
9
0
9
0
% K
% Leu:
34
0
0
0
9
0
0
0
0
0
9
25
0
17
0
% L
% Met:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
9
17
9
0
0
0
0
0
0
9
0
0
0
% N
% Pro:
17
0
17
17
0
9
0
9
9
9
0
0
9
0
17
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
25
34
25
42
42
9
17
25
17
25
25
50
9
42
% S
% Thr:
9
0
17
0
9
0
9
42
9
9
25
9
9
9
17
% T
% Val:
9
0
0
0
0
0
9
0
0
0
0
17
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _