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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMPD3
All Species:
30.3
Human Site:
S493
Identified Species:
66.67
UniProt:
Q9NY59
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NY59
NP_061137.1
655
71081
S493
F
R
K
S
T
S
S
S
S
A
A
N
P
E
E
Chimpanzee
Pan troglodytes
XP_001167790
655
71064
S493
F
R
K
S
T
S
S
S
S
A
A
N
P
E
E
Rhesus Macaque
Macaca mulatta
XP_001091683
730
78991
S493
F
R
K
S
T
S
S
S
S
T
A
N
P
E
E
Dog
Lupus familis
XP_546863
658
71463
S494
F
R
K
S
T
S
S
S
S
T
A
N
P
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJY3
655
71178
T491
F
R
K
S
T
S
S
T
S
T
A
N
P
E
E
Rat
Rattus norvegicus
O35049
655
71254
T491
F
R
K
S
T
S
S
T
S
T
A
N
P
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521026
485
53083
F343
V
F
M
G
D
L
N
F
D
N
C
S
P
D
D
Chicken
Gallus gallus
XP_429344
662
73371
S498
F
R
K
S
T
S
S
S
S
T
A
N
P
E
E
Frog
Xenopus laevis
NP_001089663
659
73316
S495
F
R
K
S
T
S
S
S
S
A
A
N
P
E
E
Zebra Danio
Brachydanio rerio
NP_001116222
684
75995
P518
F
R
R
V
T
S
C
P
A
D
E
E
K
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782298
603
68480
M440
G
N
F
N
F
D
N
M
S
P
S
D
M
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
86.3
89
N.A.
91.3
90.9
N.A.
30.9
72.8
69.5
56.7
N.A.
N.A.
N.A.
N.A.
27.3
Protein Similarity:
100
99.6
87.5
92.7
N.A.
94.5
94
N.A.
42.5
81.4
81
71.3
N.A.
N.A.
N.A.
N.A.
43.8
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
6.6
93.3
100
26.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
33.3
93.3
100
40
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
28
73
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
10
10
0
0
10
10
0
10
0
10
19
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
10
0
73
73
% E
% Phe:
82
10
10
0
10
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
73
0
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
10
0
0
0
0
10
0
0
0
0
10
0
0
% M
% Asn:
0
10
0
10
0
0
19
0
0
10
0
73
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
10
0
0
82
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
82
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
73
0
82
73
55
82
0
10
10
0
0
0
% S
% Thr:
0
0
0
0
82
0
0
19
0
46
0
0
0
10
0
% T
% Val:
10
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _