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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC2A8 All Species: 10.3
Human Site: S19 Identified Species: 17.44
UniProt: Q9NY64 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NY64 NP_055395.2 477 50819 S19 L L G P P G G S A P R G R R V
Chimpanzee Pan troglodytes XP_001148685 477 50801 S19 L L G P P G G S A P R G R R V
Rhesus Macaque Macaca mulatta XP_001096192 477 50756 S19 L L G P P G G S A P R G R R V
Dog Lupus familis XP_548395 507 54801 R31 P G D R T R V R A P Q N K R V
Cat Felis silvestris
Mouse Mus musculus Q9JIF3 477 51505 R19 L L R P P E A R T P R G R R V
Rat Rattus norvegicus Q9JJZ1 478 51440 R19 L L R S P G A R A P G G R R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507961 448 48663 D19 G P G G A P E D D C G A G S T
Chicken Gallus gallus P46896 490 54068 V19 M L A V G G A V L G S L Q F G
Frog Xenopus laevis NP_001087681 465 51027 L19 N F T F G Y A L V Y T S P V I
Zebra Danio Brachydanio rerio NP_997963 498 54767 D29 S E Q D A Y L D K V K N G K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648605 539 58395 G35 L L E S A E N G A K Y G S R Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787337 482 52038 Q43 L V T S T K G Q N A S L Y F I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FRL3 487 52883 H20 D L R R P F I H T G S W Y R M
Baker's Yeast Sacchar. cerevisiae P30606 609 66692 S67 K K S P V S T S T M Q I K S R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.6 43.2 N.A. 86.1 85.3 N.A. 61.8 23.6 41.9 56.4 N.A. 34.6 N.A. N.A. 38.1
Protein Similarity: 100 100 98.7 59.5 N.A. 92.6 92.2 N.A. 72.3 43 60.5 69.8 N.A. 53.2 N.A. N.A. 58
P-Site Identity: 100 100 100 26.6 N.A. 66.6 66.6 N.A. 6.6 13.3 0 0 N.A. 33.3 N.A. N.A. 13.3
P-Site Similarity: 100 100 100 40 N.A. 66.6 66.6 N.A. 6.6 26.6 6.6 20 N.A. 33.3 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 36.1 23.6 N.A.
Protein Similarity: N.A. N.A. N.A. 55.4 36.4 N.A.
P-Site Identity: N.A. N.A. N.A. 20 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 22 0 29 0 43 8 0 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 8 0 8 8 0 0 0 15 8 0 0 0 0 0 0 % D
% Glu: 0 8 8 0 0 15 8 0 0 0 0 0 0 0 0 % E
% Phe: 0 8 0 8 0 8 0 0 0 0 0 0 0 15 0 % F
% Gly: 8 8 29 8 15 36 29 8 0 15 15 43 15 0 8 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 15 % I
% Lys: 8 8 0 0 0 8 0 0 8 8 8 0 15 8 0 % K
% Leu: 50 58 0 0 0 0 8 8 8 0 0 15 0 0 8 % L
% Met: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % M
% Asn: 8 0 0 0 0 0 8 0 8 0 0 15 0 0 0 % N
% Pro: 8 8 0 36 43 8 0 0 0 43 0 0 8 0 0 % P
% Gln: 0 0 8 0 0 0 0 8 0 0 15 0 8 0 8 % Q
% Arg: 0 0 22 15 0 8 0 22 0 0 29 0 36 58 8 % R
% Ser: 8 0 8 22 0 8 0 29 0 0 22 8 8 15 0 % S
% Thr: 0 0 15 0 15 0 8 0 22 0 8 0 0 0 8 % T
% Val: 0 8 0 8 8 0 8 8 8 8 0 0 0 8 43 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 0 0 0 15 0 0 0 8 8 0 15 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _