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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC2A8 All Species: 21.21
Human Site: S351 Identified Species: 35.9
UniProt: Q9NY64 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NY64 NP_055395.2 477 50819 S351 Q G G P G N S S H V A I S A P
Chimpanzee Pan troglodytes XP_001148685 477 50801 S351 Q G G P G N S S H V A L S A P
Rhesus Macaque Macaca mulatta XP_001096192 477 50756 S351 Q G G P G N S S H M A L S A P
Dog Lupus familis XP_548395 507 54801 T372 K P L T P N S T M G L E S I P
Cat Felis silvestris
Mouse Mus musculus Q9JIF3 477 51505 S351 T Q S L P S N S S H V G L V P
Rat Rattus norvegicus Q9JJZ1 478 51440 S352 Q S G P S N S S H V G L L V P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507961 448 48663 L327 N S S H P G S L T T L N P E T
Chicken Gallus gallus P46896 490 54068 S364 L D Q M P W M S Y L S I V A I
Frog Xenopus laevis NP_001087681 465 51027 T333 V D I N H N S T N R T M S I S
Zebra Danio Brachydanio rerio NP_997963 498 54767 S368 V M K P N N S S M T S V L T D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648605 539 58395 V406 I S T T A I G V Y F F L Q K Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787337 482 52038 Y357 S A T F G L Y Y Q V T G D D V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FRL3 487 52883 A365 I S L V I V A A A F Y L K E F
Baker's Yeast Sacchar. cerevisiae P30606 609 66692 F451 F H F L G I K F N G A D A V V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.6 43.2 N.A. 86.1 85.3 N.A. 61.8 23.6 41.9 56.4 N.A. 34.6 N.A. N.A. 38.1
Protein Similarity: 100 100 98.7 59.5 N.A. 92.6 92.2 N.A. 72.3 43 60.5 69.8 N.A. 53.2 N.A. N.A. 58
P-Site Identity: 100 93.3 86.6 26.6 N.A. 13.3 60 N.A. 6.6 20 20 26.6 N.A. 0 N.A. N.A. 13.3
P-Site Similarity: 100 100 100 40 N.A. 26.6 66.6 N.A. 6.6 40 40 40 N.A. 13.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. 36.1 23.6 N.A.
Protein Similarity: N.A. N.A. N.A. 55.4 36.4 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 8 0 8 8 8 0 29 0 8 29 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 0 0 0 0 0 0 0 0 0 8 8 8 8 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 8 0 15 0 % E
% Phe: 8 0 8 8 0 0 0 8 0 15 8 0 0 0 8 % F
% Gly: 0 22 29 0 36 8 8 0 0 15 8 15 0 0 0 % G
% His: 0 8 0 8 8 0 0 0 29 8 0 0 0 0 0 % H
% Ile: 15 0 8 0 8 15 0 0 0 0 0 15 0 15 8 % I
% Lys: 8 0 8 0 0 0 8 0 0 0 0 0 8 8 0 % K
% Leu: 8 0 15 15 0 8 0 8 0 8 15 36 22 0 0 % L
% Met: 0 8 0 8 0 0 8 0 15 8 0 8 0 0 0 % M
% Asn: 8 0 0 8 8 50 8 0 15 0 0 8 0 0 0 % N
% Pro: 0 8 0 36 29 0 0 0 0 0 0 0 8 0 43 % P
% Gln: 29 8 8 0 0 0 0 0 8 0 0 0 8 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % R
% Ser: 8 29 15 0 8 8 58 50 8 0 15 0 36 0 8 % S
% Thr: 8 0 15 15 0 0 0 15 8 15 15 0 0 8 8 % T
% Val: 15 0 0 8 0 8 0 8 0 29 8 8 8 22 15 % V
% Trp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 8 15 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _