KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TUBA8
All Species:
45.15
Human Site:
S439
Identified Species:
76.41
UniProt:
Q9NY65
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NY65
NP_061816.1
449
50094
S439
Y
E
E
V
G
T
D
S
F
E
E
E
N
E
G
Chimpanzee
Pan troglodytes
Q5R1W4
451
50117
S439
Y
E
E
V
G
V
D
S
V
E
G
E
G
E
E
Rhesus Macaque
Macaca mulatta
XP_001104090
488
53695
S478
Y
E
E
V
G
T
D
S
F
E
E
E
N
E
G
Dog
Lupus familis
XP_543889
449
50003
S439
Y
E
E
V
G
T
D
S
F
E
E
E
N
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJZ2
449
50033
S439
Y
E
E
V
G
T
D
S
F
E
E
E
N
E
G
Rat
Rattus norvegicus
Q6AY56
449
50019
S439
Y
E
E
V
G
T
D
S
F
E
E
E
N
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507277
587
64510
S577
Y
E
E
V
G
T
D
S
F
E
E
E
N
E
G
Chicken
Gallus gallus
P08070
446
49780
L436
Y
D
E
V
A
T
D
L
F
E
D
E
N
E
A
Frog
Xenopus laevis
P08537
449
49861
S439
Y
E
E
V
G
A
D
S
A
D
A
E
D
E
G
Zebra Danio
Brachydanio rerio
NP_997937
449
50032
S439
Y
E
E
V
G
A
D
S
T
E
D
G
E
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P06603
450
49890
S439
Y
E
E
V
G
M
D
S
G
D
G
E
G
E
G
Honey Bee
Apis mellifera
XP_391936
450
49946
S439
Y
E
E
V
G
M
D
S
A
E
G
E
G
E
G
Nematode Worm
Caenorhab. elegans
P34690
448
49895
S437
Y
E
E
V
G
A
D
S
N
E
G
G
E
E
E
Sea Urchin
Strong. purpuratus
XP_780117
450
50180
S439
Y
E
E
V
G
I
D
S
C
D
A
E
A
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.8
92
98.8
N.A.
99.3
99.1
N.A.
71.8
86.6
89.7
89.7
N.A.
90.8
91.3
86.1
86.4
Protein Similarity:
100
94
92
99.3
N.A.
99.5
99.5
N.A.
75.1
92.6
94.6
95
N.A.
94.2
94.2
93.5
93.3
P-Site Identity:
100
66.6
100
100
N.A.
100
100
N.A.
100
66.6
66.6
66.6
N.A.
66.6
73.3
60
60
P-Site Similarity:
100
66.6
100
100
N.A.
100
100
N.A.
100
80
80
73.3
N.A.
73.3
73.3
60
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
22
0
0
15
0
15
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
100
0
0
22
15
0
8
0
8
% D
% Glu:
0
93
100
0
0
0
0
0
0
79
43
86
15
100
15
% E
% Phe:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
93
0
0
0
8
0
29
15
22
0
72
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
50
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
93
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
50
0
0
8
0
0
0
0
0
0
% T
% Val:
0
0
0
100
0
8
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _