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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC5A4
All Species:
27.88
Human Site:
S460
Identified Species:
76.67
UniProt:
Q9NY91
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NY91
NP_055042.1
659
72456
S460
I
H
Y
T
E
S
I
S
S
Y
L
G
P
P
I
Chimpanzee
Pan troglodytes
XP_525573
659
72556
S460
I
H
Y
T
E
S
I
S
S
Y
L
G
P
P
I
Rhesus Macaque
Macaca mulatta
XP_001112250
659
72762
S460
I
H
Y
T
E
S
I
S
S
Y
L
G
P
P
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9ET37
656
71820
S460
V
H
Y
T
E
A
I
S
S
Y
L
G
P
P
I
Rat
Rattus norvegicus
P53790
665
73048
T460
F
D
Y
I
Q
S
I
T
S
Y
L
G
P
P
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505333
661
72904
T455
F
D
Y
I
Q
S
I
T
S
Y
L
G
P
P
I
Chicken
Gallus gallus
XP_415247
658
72349
T456
F
D
Y
I
Q
S
V
T
S
Y
L
G
P
P
I
Frog
Xenopus laevis
NP_001087699
617
66972
D448
A
Q
G
G
Q
L
F
D
Y
I
Q
S
V
A
S
Zebra Danio
Brachydanio rerio
A8WHP3
657
72206
T454
F
D
Y
I
Q
A
I
T
S
F
L
S
P
P
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.4
N.A.
N.A.
78.7
71.8
N.A.
71.7
67.8
54.1
53.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
97.5
N.A.
N.A.
88.6
85.2
N.A.
85.1
82
74
73.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
86.6
66.6
N.A.
66.6
60
0
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
100
80
N.A.
80
80
6.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
23
0
0
0
0
0
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
45
0
0
0
0
0
12
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
45
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
45
0
0
0
0
0
12
0
0
12
0
0
0
0
0
% F
% Gly:
0
0
12
12
0
0
0
0
0
0
0
78
0
0
0
% G
% His:
0
45
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
34
0
0
45
0
0
78
0
0
12
0
0
0
0
89
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
12
0
0
0
0
89
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
89
89
0
% P
% Gln:
0
12
0
0
56
0
0
0
0
0
12
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
67
0
45
89
0
0
23
0
0
12
% S
% Thr:
0
0
0
45
0
0
0
45
0
0
0
0
0
0
0
% T
% Val:
12
0
0
0
0
0
12
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
89
0
0
0
0
0
12
78
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _