KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX56
All Species:
20.61
Human Site:
S405
Identified Species:
34.87
UniProt:
Q9NY93
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NY93
NP_061955.1
547
61590
S405
G
K
I
E
E
L
L
S
G
E
N
R
G
P
I
Chimpanzee
Pan troglodytes
XP_001145021
547
61601
S405
G
K
I
E
E
L
L
S
G
E
N
R
G
P
I
Rhesus Macaque
Macaca mulatta
XP_001090331
546
61504
S405
G
K
I
E
E
L
L
S
G
E
N
R
G
P
I
Dog
Lupus familis
XP_850575
570
63900
S430
D
T
I
E
E
L
L
S
G
E
N
R
A
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9D0R4
546
61194
S405
G
K
I
E
D
L
L
S
G
E
G
E
A
P
I
Rat
Rattus norvegicus
NP_001004211
482
54434
R367
E
S
F
R
Y
R
C
R
D
A
M
R
S
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084622
552
62481
G403
A
G
V
E
E
A
L
G
G
G
V
P
D
E
Y
Zebra Danio
Brachydanio rerio
NP_001003876
557
62952
T407
S
E
V
E
N
A
L
T
G
D
S
N
N
C
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523434
560
62865
C403
D
S
V
E
K
K
L
C
D
S
F
A
A
Q
E
Honey Bee
Apis mellifera
XP_391920
547
62199
Q404
D
V
E
V
E
L
K
Q
C
Y
N
C
D
K
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195983
520
58662
I405
D
N
V
E
Q
E
L
I
G
D
D
G
T
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SW44
626
69483
A456
E
D
I
K
S
F
L
A
S
D
K
N
K
D
I
Baker's Yeast
Sacchar. cerevisiae
Q06218
594
68041
T443
H
K
P
S
M
L
Q
T
A
K
K
D
E
R
I
Red Bread Mold
Neurospora crassa
Q7S6F3
676
76598
Q508
H
K
P
T
S
I
K
Q
C
E
K
D
E
K
V
Conservation
Percent
Protein Identity:
100
99.6
98.3
78
N.A.
90.8
79.8
N.A.
N.A.
N.A.
66.3
64.2
N.A.
47.1
50.8
N.A.
51.1
Protein Similarity:
100
99.8
99.2
84.5
N.A.
94.8
83.9
N.A.
N.A.
N.A.
80.9
80.2
N.A.
65.8
68.1
N.A.
69.6
P-Site Identity:
100
100
100
73.3
N.A.
73.3
6.6
N.A.
N.A.
N.A.
26.6
20
N.A.
13.3
20
N.A.
26.6
P-Site Similarity:
100
100
100
80
N.A.
80
6.6
N.A.
N.A.
N.A.
33.3
60
N.A.
26.6
26.6
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.7
43.1
37.1
Protein Similarity:
N.A.
N.A.
N.A.
55.1
62.6
52.3
P-Site Identity:
N.A.
N.A.
N.A.
20
20
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
40
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
15
0
8
8
8
0
8
22
0
0
% A
% Cys:
0
0
0
0
0
0
8
8
15
0
0
8
0
8
0
% C
% Asp:
29
8
0
0
8
0
0
0
15
22
8
15
15
8
0
% D
% Glu:
15
8
8
65
43
8
0
0
0
43
0
8
15
8
8
% E
% Phe:
0
0
8
0
0
8
0
0
0
0
8
0
0
0
0
% F
% Gly:
29
8
0
0
0
0
0
8
58
8
8
8
22
0
0
% G
% His:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
43
0
0
8
0
8
0
0
0
0
0
0
43
% I
% Lys:
0
43
0
8
8
8
15
0
0
8
22
0
8
15
0
% K
% Leu:
0
0
0
0
0
50
72
0
0
0
0
0
0
0
15
% L
% Met:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
0
0
0
36
15
8
0
0
% N
% Pro:
0
0
15
0
0
0
0
0
0
0
0
8
0
43
0
% P
% Gln:
0
0
0
0
8
0
8
15
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
8
0
8
0
8
0
0
0
36
0
8
0
% R
% Ser:
8
15
0
8
15
0
0
36
8
8
8
0
8
0
0
% S
% Thr:
0
8
0
8
0
0
0
15
0
0
0
0
8
0
8
% T
% Val:
0
8
29
8
0
0
0
0
0
0
8
0
0
8
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _