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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABI2 All Species: 16.97
Human Site: S246 Identified Species: 46.67
UniProt: Q9NYB9 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYB9 NP_005750.4 513 55663 S246 R T Y S S S G S S G G S H P S
Chimpanzee Pan troglodytes XP_001173242 513 55664 S246 R T Y S S S G S S G G S H P S
Rhesus Macaque Macaca mulatta XP_001102942 513 55634 S246 R T Y S S S G S S G G S H P S
Dog Lupus familis XP_545606 513 55531 S246 R T Y S S S G S S G G S H P S
Cat Felis silvestris
Mouse Mus musculus P62484 446 49369 G182 P P S P P M S G K G T L G R H
Rat Rattus norvegicus Q9QZM5 476 51686 P212 P N D Y M T S P A R L G S Q H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232729 522 57649 G246 R T Y S G S S G G S H P S S R
Frog Xenopus laevis Q6NRD3 826 88022 S303 K K R H S F T S L T M S N K S
Zebra Danio Brachydanio rerio A5D8S5 867 91614 T576 M H V T S Q M T V N Q A R N A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 99.2 98.6 N.A. 86.3 64.1 N.A. N.A. 78.1 20.8 21.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.6 99.4 99 N.A. 86.7 74.8 N.A. N.A. 81.2 33.2 32.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 6.6 0 N.A. N.A. 33.3 26.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 6.6 13.3 N.A. N.A. 33.3 40 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 12 0 0 12 0 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 12 0 45 23 12 56 45 12 12 0 0 % G
% His: 0 12 0 12 0 0 0 0 0 0 12 0 45 0 23 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 12 12 0 0 0 0 0 0 12 0 0 0 0 12 0 % K
% Leu: 0 0 0 0 0 0 0 0 12 0 12 12 0 0 0 % L
% Met: 12 0 0 0 12 12 12 0 0 0 12 0 0 0 0 % M
% Asn: 0 12 0 0 0 0 0 0 0 12 0 0 12 12 0 % N
% Pro: 23 12 0 12 12 0 0 12 0 0 0 12 0 45 0 % P
% Gln: 0 0 0 0 0 12 0 0 0 0 12 0 0 12 0 % Q
% Arg: 56 0 12 0 0 0 0 0 0 12 0 0 12 12 12 % R
% Ser: 0 0 12 56 67 56 34 56 45 12 0 56 23 12 56 % S
% Thr: 0 56 0 12 0 12 12 12 0 12 12 0 0 0 0 % T
% Val: 0 0 12 0 0 0 0 0 12 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 56 12 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _