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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM53C
All Species:
19.09
Human Site:
S45
Identified Species:
52.5
UniProt:
Q9NYF3
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYF3
NP_001129119.1
392
43091
S45
G
N
S
F
Q
L
V
S
E
G
A
S
W
R
G
Chimpanzee
Pan troglodytes
XP_001171129
392
42994
S45
G
N
P
F
Q
L
V
S
E
G
A
S
W
R
G
Rhesus Macaque
Macaca mulatta
XP_001112778
392
43022
S45
G
N
P
F
Q
L
V
S
E
G
A
S
W
R
G
Dog
Lupus familis
XP_851197
392
42783
S45
G
N
P
F
Q
L
V
S
E
G
A
S
W
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXQ8
393
43242
S45
G
D
P
F
Q
L
V
S
E
G
A
S
W
R
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509798
323
35914
Chicken
Gallus gallus
Q5ZKN5
418
46229
E45
L
F
S
F
E
I
N
E
D
S
P
W
K
A
L
Frog
Xenopus laevis
NP_001089742
373
41666
S45
S
S
P
Y
H
F
V
S
E
D
R
S
W
G
L
Zebra Danio
Brachydanio rerio
NP_001104709
374
39956
L45
H
L
P
E
G
D
A
L
N
R
P
L
A
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.7
96.1
N.A.
94.4
N.A.
N.A.
24.7
31.3
52.5
36.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
99.2
97.1
N.A.
96.6
N.A.
N.A.
37.2
47.6
62.7
46.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
93.3
N.A.
86.6
N.A.
N.A.
0
13.3
33.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
93.3
N.A.
N.A.
0
33.3
46.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
12
0
0
0
56
0
12
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
12
0
0
12
12
0
0
0
0
0
% D
% Glu:
0
0
0
12
12
0
0
12
67
0
0
0
0
0
0
% E
% Phe:
0
12
0
67
0
12
0
0
0
0
0
0
0
0
0
% F
% Gly:
56
0
0
0
12
0
0
0
0
56
0
0
0
12
56
% G
% His:
12
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% K
% Leu:
12
12
0
0
0
56
0
12
0
0
0
12
0
0
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
45
0
0
0
0
12
0
12
0
0
0
0
0
0
% N
% Pro:
0
0
67
0
0
0
0
0
0
0
23
0
0
12
0
% P
% Gln:
0
0
0
0
56
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
12
12
0
0
56
0
% R
% Ser:
12
12
23
0
0
0
0
67
0
12
0
67
0
0
12
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
67
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
12
67
0
0
% W
% Tyr:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _