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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZDHHC3
All Species:
11.82
Human Site:
S218
Identified Species:
23.64
UniProt:
Q9NYG2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYG2
NP_001128651.1
327
37338
S218
E
M
A
E
T
G
I
S
L
H
E
K
M
Q
P
Chimpanzee
Pan troglodytes
XP_516405
327
37271
S218
E
M
A
E
T
G
I
S
L
H
E
K
M
Q
P
Rhesus Macaque
Macaca mulatta
XP_001114737
327
37242
S218
E
M
A
E
A
G
I
S
L
H
E
K
M
Q
P
Dog
Lupus familis
XP_851982
327
37241
S218
G
T
A
E
A
R
L
S
L
H
E
K
K
Q
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R173
299
34023
F194
L
I
M
V
G
F
H
F
L
H
C
F
E
E
D
Rat
Rattus norvegicus
Q923G5
308
35213
Q204
F
I
S
C
V
R
G
Q
W
T
E
C
S
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517044
328
37512
P218
P
R
I
K
A
G
V
P
F
Y
L
I
P
K
P
Chicken
Gallus gallus
XP_418804
323
36369
I217
P
T
T
V
I
L
L
I
L
L
C
F
E
A
L
Frog
Xenopus laevis
Q5FWL7
338
39422
A220
V
L
F
L
L
F
V
A
L
M
F
F
I
S
L
Zebra Danio
Brachydanio rerio
NP_001071225
300
34074
V196
L
M
V
A
F
H
F
V
F
C
F
E
E
D
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8I0G4
403
46434
D215
D
M
N
K
K
Q
Y
D
S
I
D
S
V
I
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94C49
302
33530
P198
D
G
D
I
T
V
S
P
G
S
L
A
A
S
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99
96.3
N.A.
88.9
56.5
N.A.
85.6
74.6
22.1
74.9
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
100
99.6
99.3
97.2
N.A.
89.9
70
N.A.
89.9
80.4
34.9
80.4
N.A.
N.A.
N.A.
35.7
N.A.
P-Site Identity:
100
100
93.3
60
N.A.
13.3
6.6
N.A.
13.3
6.6
6.6
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
93.3
66.6
N.A.
26.6
20
N.A.
40
13.3
33.3
13.3
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
34
9
25
0
0
9
0
0
0
9
9
9
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
9
17
9
0
0
0
% C
% Asp:
17
0
9
0
0
0
0
9
0
0
9
0
0
17
9
% D
% Glu:
25
0
0
34
0
0
0
0
0
0
42
9
25
9
0
% E
% Phe:
9
0
9
0
9
17
9
9
17
0
17
25
0
0
17
% F
% Gly:
9
9
0
0
9
34
9
0
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
9
9
0
0
42
0
0
0
0
0
% H
% Ile:
0
17
9
9
9
0
25
9
0
9
0
9
9
9
0
% I
% Lys:
0
0
0
17
9
0
0
0
0
0
0
34
9
9
0
% K
% Leu:
17
9
0
9
9
9
17
0
59
9
17
0
0
0
17
% L
% Met:
0
42
9
0
0
0
0
0
0
9
0
0
25
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
17
0
0
0
0
0
0
17
0
0
0
0
9
0
42
% P
% Gln:
0
0
0
0
0
9
0
9
0
0
0
0
0
34
9
% Q
% Arg:
0
9
0
0
0
17
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
0
0
0
9
34
9
9
0
9
9
17
0
% S
% Thr:
0
17
9
0
25
0
0
0
0
9
0
0
0
0
0
% T
% Val:
9
0
9
17
9
9
17
9
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _