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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZDHHC3
All Species:
19.39
Human Site:
T259
Identified Species:
38.79
UniProt:
Q9NYG2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYG2
NP_001128651.1
327
37338
T259
G
L
L
F
L
I
F
T
S
V
M
F
G
T
Q
Chimpanzee
Pan troglodytes
XP_516405
327
37271
T259
G
L
L
F
L
I
F
T
S
V
M
F
G
T
Q
Rhesus Macaque
Macaca mulatta
XP_001114737
327
37242
T259
G
L
L
F
L
I
F
T
S
V
M
F
G
T
Q
Dog
Lupus familis
XP_851982
327
37241
T259
G
L
L
F
L
I
F
T
S
V
M
F
G
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8R173
299
34023
S232
L
L
F
L
I
F
T
S
V
M
F
G
T
Q
V
Rat
Rattus norvegicus
Q923G5
308
35213
I242
A
V
M
F
G
T
Q
I
H
S
I
C
N
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517044
328
37512
T260
G
L
L
F
L
I
F
T
S
V
M
F
G
T
Q
Chicken
Gallus gallus
XP_418804
323
36369
P256
E
R
L
K
K
Q
K
P
T
W
E
R
T
S
G
Frog
Xenopus laevis
Q5FWL7
338
39422
Q272
G
I
R
R
N
L
E
Q
V
F
G
K
E
R
K
Zebra Danio
Brachydanio rerio
NP_001071225
300
34074
V234
L
F
L
I
F
T
A
V
M
F
G
T
Q
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q8I0G4
403
46434
L253
S
C
M
F
S
L
S
L
S
F
L
F
F
Y
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94C49
302
33530
I236
V
A
R
N
T
T
T
I
E
A
Y
E
K
H
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99
96.3
N.A.
88.9
56.5
N.A.
85.6
74.6
22.1
74.9
N.A.
N.A.
N.A.
21
N.A.
Protein Similarity:
100
99.6
99.3
97.2
N.A.
89.9
70
N.A.
89.9
80.4
34.9
80.4
N.A.
N.A.
N.A.
35.7
N.A.
P-Site Identity:
100
100
100
100
N.A.
6.6
6.6
N.A.
100
6.6
6.6
6.6
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
26.6
33.3
N.A.
100
20
26.6
6.6
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
0
0
9
0
0
9
0
0
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% D
% Glu:
9
0
0
0
0
0
9
0
9
0
9
9
9
0
9
% E
% Phe:
0
9
9
59
9
9
42
0
0
25
9
50
9
0
0
% F
% Gly:
50
0
0
0
9
0
0
0
0
0
17
9
42
0
9
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
17
% H
% Ile:
0
9
0
9
9
42
0
17
0
0
9
0
0
0
0
% I
% Lys:
0
0
0
9
9
0
9
0
0
0
0
9
9
0
9
% K
% Leu:
17
50
59
9
42
17
0
9
0
0
9
0
0
0
0
% L
% Met:
0
0
17
0
0
0
0
0
9
9
42
0
0
0
0
% M
% Asn:
0
0
0
9
9
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
9
9
0
0
0
0
9
9
42
% Q
% Arg:
0
9
17
9
0
0
0
0
0
0
0
9
0
9
0
% R
% Ser:
9
0
0
0
9
0
9
9
50
9
0
0
0
9
0
% S
% Thr:
0
0
0
0
9
25
17
42
9
0
0
9
17
42
9
% T
% Val:
9
9
0
0
0
0
0
9
17
42
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _