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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNK4 All Species: 16.67
Human Site: S319 Identified Species: 36.67
UniProt: Q9NYG8 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYG8 NP_201567.1 393 42704 S319 Q P L G R P R S P S P P E K A
Chimpanzee Pan troglodytes XP_001164319 396 43154 S322 Q P L G R P R S P S P P E K A
Rhesus Macaque Macaca mulatta XP_001115027 432 46346 S358 Q P L G R P R S P S P P K K A
Dog Lupus familis XP_854939 663 69998 K594 P P S P L P V K A E P P S P S
Cat Felis silvestris
Mouse Mus musculus O88454 398 43033 S324 E P A G R P G S P A P A E K V
Rat Rattus norvegicus Q9JIS4 538 59782 R385 R R L G L D Q R A H S L D M L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510388 626 67934 A570 R K L S A E L A V N H N Q E L
Chicken Gallus gallus XP_426457 527 58809 T359 D K L Q R A A T I R S M E R R
Frog Xenopus laevis Q63ZI0 374 42700 S304 C S C M C Y R S H E Y T S R M
Zebra Danio Brachydanio rerio XP_688186 490 54952 S447 M P C K R T L S V N F T D E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17185 329 36973 D286 F G R L P L S D N V S L A S C
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.6 90 52.3 N.A. 82.6 34.5 N.A. 27 35.2 24.6 33 N.A. N.A. N.A. 27.9 N.A.
Protein Similarity: 100 93.1 90.5 54.4 N.A. 88.6 47.5 N.A. 36.9 48.3 43.7 47.9 N.A. N.A. N.A. 44.2 N.A.
P-Site Identity: 100 100 93.3 26.6 N.A. 60 13.3 N.A. 6.6 20 13.3 20 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 100 33.3 N.A. 73.3 33.3 N.A. 40 33.3 20 40 N.A. N.A. N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 10 10 10 10 19 10 0 10 10 0 28 % A
% Cys: 10 0 19 0 10 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 10 0 0 0 0 10 0 10 0 0 0 0 19 0 0 % D
% Glu: 10 0 0 0 0 10 0 0 0 19 0 0 37 19 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 0 10 0 46 0 0 10 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 10 10 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 19 0 10 0 0 0 10 0 0 0 0 10 37 0 % K
% Leu: 0 0 55 10 19 10 19 0 0 0 0 19 0 0 28 % L
% Met: 10 0 0 10 0 0 0 0 0 0 0 10 0 10 10 % M
% Asn: 0 0 0 0 0 0 0 0 10 19 0 10 0 0 0 % N
% Pro: 10 55 0 10 10 46 0 0 37 0 46 37 0 10 0 % P
% Gln: 28 0 0 10 0 0 10 0 0 0 0 0 10 0 0 % Q
% Arg: 19 10 10 0 55 0 37 10 0 10 0 0 0 19 10 % R
% Ser: 0 10 10 10 0 0 10 55 0 28 28 0 19 10 10 % S
% Thr: 0 0 0 0 0 10 0 10 0 0 0 19 0 0 0 % T
% Val: 0 0 0 0 0 0 10 0 19 10 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _