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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK4
All Species:
21.82
Human Site:
T353
Identified Species:
48
UniProt:
Q9NYG8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYG8
NP_201567.1
393
42704
T353
F
I
D
E
S
S
D
T
Q
S
E
R
G
C
P
Chimpanzee
Pan troglodytes
XP_001164319
396
43154
T356
F
I
D
E
S
S
D
T
Q
S
E
R
G
C
P
Rhesus Macaque
Macaca mulatta
XP_001115027
432
46346
T392
F
I
D
E
S
S
D
T
Q
S
E
R
G
C
P
Dog
Lupus familis
XP_854939
663
69998
T628
F
I
D
E
S
S
D
T
Q
S
E
R
G
C
A
Cat
Felis silvestris
Mouse
Mus musculus
O88454
398
43033
T358
F
I
D
E
S
S
D
T
Q
S
E
R
G
C
A
Rat
Rattus norvegicus
Q9JIS4
538
59782
R419
S
Q
E
S
I
N
N
R
P
N
N
L
R
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510388
626
67934
S604
P
P
L
T
K
T
D
S
I
Y
L
N
G
L
T
Chicken
Gallus gallus
XP_426457
527
58809
T393
S
V
F
T
A
L
E
T
G
R
F
K
A
S
S
Frog
Xenopus laevis
Q63ZI0
374
42700
S338
S
Y
K
I
E
E
I
S
P
S
T
L
K
N
S
Zebra Danio
Brachydanio rerio
XP_688186
490
54952
S481
T
P
D
C
P
D
C
S
E
I
S
I
I
E
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17185
329
36973
F320
P
H
G
G
P
P
T
F
S
G
M
T
T
R
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.6
90
52.3
N.A.
82.6
34.5
N.A.
27
35.2
24.6
33
N.A.
N.A.
N.A.
27.9
N.A.
Protein Similarity:
100
93.1
90.5
54.4
N.A.
88.6
47.5
N.A.
36.9
48.3
43.7
47.9
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
0
N.A.
13.3
6.6
6.6
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
26.6
N.A.
26.6
33.3
13.3
20
N.A.
N.A.
N.A.
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
19
% A
% Cys:
0
0
0
10
0
0
10
0
0
0
0
0
0
46
0
% C
% Asp:
0
0
55
0
0
10
55
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
46
10
10
10
0
10
0
46
0
0
10
0
% E
% Phe:
46
0
10
0
0
0
0
10
0
0
10
0
0
0
0
% F
% Gly:
0
0
10
10
0
0
0
0
10
10
0
0
55
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
46
0
10
10
0
10
0
10
10
0
10
10
0
0
% I
% Lys:
0
0
10
0
10
0
0
0
0
0
0
10
10
0
10
% K
% Leu:
0
0
10
0
0
10
0
0
0
0
10
19
0
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
10
0
0
10
10
10
0
10
0
% N
% Pro:
19
19
0
0
19
10
0
0
19
0
0
0
0
0
37
% P
% Gln:
0
10
0
0
0
0
0
0
46
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
10
0
46
10
10
0
% R
% Ser:
28
0
0
10
46
46
0
28
10
55
10
0
0
10
19
% S
% Thr:
10
0
0
19
0
10
10
55
0
0
10
10
10
0
10
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _