KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLL3
All Species:
26.67
Human Site:
S121
Identified Species:
53.33
UniProt:
Q9NYJ7
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYJ7
NP_982353.1
618
64618
S121
D
A
W
P
G
T
F
S
F
I
I
E
T
W
R
Chimpanzee
Pan troglodytes
XP_510318
685
74575
S116
F
T
W
P
G
T
F
S
L
I
I
E
A
W
H
Rhesus Macaque
Macaca mulatta
XP_001088937
587
61355
S121
D
A
W
P
G
T
F
S
L
I
I
E
T
W
R
Dog
Lupus familis
XP_855351
426
44834
S36
V
F
E
L
Q
I
H
S
F
G
P
G
P
G
P
Cat
Felis silvestris
Mouse
Mus musculus
O88516
592
62051
S119
D
A
W
P
G
T
F
S
L
V
I
E
T
W
R
Rat
Rattus norvegicus
O88671
589
61406
S119
D
A
W
P
G
T
F
S
L
I
I
E
T
W
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421132
798
87862
S225
F
T
W
P
G
T
F
S
L
I
I
Q
A
W
H
Frog
Xenopus laevis
NP_001079551
642
70637
A113
E
S
W
T
T
N
S
A
E
Q
S
T
E
N
P
Zebra Danio
Brachydanio rerio
Q9IAT6
664
72529
S110
E
T
W
N
A
E
T
S
D
Q
S
T
E
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10041
833
88822
S127
F
S
W
P
G
T
F
S
L
I
V
E
A
W
H
Honey Bee
Apis mellifera
XP_393831
1119
119736
S352
F
T
W
P
G
T
F
S
L
I
V
E
A
Y
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P10079
1064
112055
G205
Y
A
C
T
C
P
P
G
F
T
G
R
N
C
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.9
91
61.3
N.A.
79.7
78.9
N.A.
N.A.
27.4
38.1
36.1
N.A.
25.8
23.1
N.A.
21.9
Protein Similarity:
100
43.2
92
63.9
N.A.
85.2
84.1
N.A.
N.A.
40.9
52
50.4
N.A.
38.5
33.4
N.A.
32.1
P-Site Identity:
100
66.6
93.3
13.3
N.A.
86.6
93.3
N.A.
N.A.
60
6.6
13.3
N.A.
60
53.3
N.A.
13.3
P-Site Similarity:
100
66.6
93.3
13.3
N.A.
93.3
93.3
N.A.
N.A.
66.6
26.6
20
N.A.
73.3
66.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
42
0
0
9
0
0
9
0
0
0
0
34
0
0
% A
% Cys:
0
0
9
0
9
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
34
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% D
% Glu:
17
0
9
0
0
9
0
0
9
0
0
59
17
0
9
% E
% Phe:
34
9
0
0
0
0
67
0
25
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
67
0
0
9
0
9
9
9
0
9
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
34
% H
% Ile:
0
0
0
0
0
9
0
0
0
59
50
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
9
0
0
0
0
59
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
9
0
0
0
0
0
0
9
17
9
% N
% Pro:
0
0
0
67
0
9
9
0
0
0
9
0
9
0
17
% P
% Gln:
0
0
0
0
9
0
0
0
0
17
0
9
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
34
% R
% Ser:
0
17
0
0
0
0
9
84
0
0
17
0
0
0
0
% S
% Thr:
0
34
0
17
9
67
9
0
0
9
0
17
34
0
0
% T
% Val:
9
0
0
0
0
0
0
0
0
9
17
0
0
0
0
% V
% Trp:
0
0
84
0
0
0
0
0
0
0
0
0
0
59
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _