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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLL3
All Species:
0
Human Site:
T549
Identified Species:
0
UniProt:
Q9NYJ7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYJ7
NP_982353.1
618
64618
T549
D
A
L
N
N
L
R
T
Q
E
G
S
G
D
G
Chimpanzee
Pan troglodytes
XP_510318
685
74575
N589
A
A
Q
L
K
N
T
N
Q
K
K
E
L
E
V
Rhesus Macaque
Macaca mulatta
XP_001088937
587
61355
G519
L
V
H
V
R
R
R
G
H
A
Q
D
A
G
S
Dog
Lupus familis
XP_855351
426
44834
Q358
C
H
C
P
P
G
F
Q
G
S
N
C
E
K
R
Cat
Felis silvestris
Mouse
Mus musculus
O88516
592
62051
G519
H
V
R
R
R
G
P
G
Q
D
T
G
T
R
L
Rat
Rattus norvegicus
O88671
589
61406
R519
L
L
L
I
H
V
R
R
R
G
P
G
R
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421132
798
87862
L714
D
L
E
V
D
C
G
L
E
K
S
N
Y
K
P
Frog
Xenopus laevis
NP_001079551
642
70637
N574
E
P
H
F
K
M
P
N
P
D
Y
L
R
E
K
Zebra Danio
Brachydanio rerio
Q9IAT6
664
72529
G567
L
S
P
T
S
P
L
G
R
E
K
E
A
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10041
833
88822
D687
N
I
I
K
N
T
W
D
K
S
V
N
N
I
C
Honey Bee
Apis mellifera
XP_393831
1119
119736
K957
T
G
D
A
H
M
I
K
N
T
W
T
A
N
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P10079
1064
112055
C949
E
G
M
W
Y
N
E
C
N
D
Q
V
T
I
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.9
91
61.3
N.A.
79.7
78.9
N.A.
N.A.
27.4
38.1
36.1
N.A.
25.8
23.1
N.A.
21.9
Protein Similarity:
100
43.2
92
63.9
N.A.
85.2
84.1
N.A.
N.A.
40.9
52
50.4
N.A.
38.5
33.4
N.A.
32.1
P-Site Identity:
100
13.3
6.6
0
N.A.
6.6
20
N.A.
N.A.
6.6
0
6.6
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
26.6
6.6
0
N.A.
13.3
40
N.A.
N.A.
33.3
26.6
26.6
N.A.
33.3
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
0
9
0
0
0
0
0
9
0
0
25
0
0
% A
% Cys:
9
0
9
0
0
9
0
9
0
0
0
9
0
0
9
% C
% Asp:
17
0
9
0
9
0
0
9
0
25
0
9
0
17
0
% D
% Glu:
17
0
9
0
0
0
9
0
9
17
0
17
9
17
0
% E
% Phe:
0
0
0
9
0
0
9
0
0
0
0
0
0
9
0
% F
% Gly:
0
17
0
0
0
17
9
25
9
9
9
17
9
9
9
% G
% His:
9
9
17
0
17
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
9
9
9
0
0
9
0
0
0
0
0
0
17
0
% I
% Lys:
0
0
0
9
17
0
0
9
9
17
17
0
0
17
17
% K
% Leu:
25
17
17
9
0
9
9
9
0
0
0
9
9
0
17
% L
% Met:
0
0
9
0
0
17
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
9
17
17
0
17
17
0
9
17
9
9
0
% N
% Pro:
0
9
9
9
9
9
17
0
9
0
9
0
0
0
9
% P
% Gln:
0
0
9
0
0
0
0
9
25
0
17
0
0
0
0
% Q
% Arg:
0
0
9
9
17
9
25
9
17
0
0
0
17
9
9
% R
% Ser:
0
9
0
0
9
0
0
0
0
17
9
9
0
0
9
% S
% Thr:
9
0
0
9
0
9
9
9
0
9
9
9
17
0
17
% T
% Val:
0
17
0
17
0
9
0
0
0
0
9
9
0
0
9
% V
% Trp:
0
0
0
9
0
0
9
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
9
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _