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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TLR7 All Species: 7.88
Human Site: S1011 Identified Species: 24.76
UniProt: Q9NYK1 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYK1 NP_057646.1 1049 120922 S1011 R K R L C G S S V L E W P T N
Chimpanzee Pan troglodytes B3Y613 784 89806 Q747 I E K K A I P Q R F C K L R K
Rhesus Macaque Macaca mulatta B3Y618 784 90053 Q747 I E K K A I P Q R F C K L R K
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P58681 1050 121818 S1012 R K R L C R S S V L E W P A N
Rat Rattus norvegicus Q9QX05 835 96053 N798 T Y L E W E D N A L G R H I F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515229 1059 121608 S1021 R K R L C G R S V L E W P A N
Chicken Gallus gallus Q9DD78 793 90748 K756 I Q S Q A I P K R F C K L R K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665957 1231 140895 R1188 H S K Y L R L R K R L Y K K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 24.6 23.6 N.A. N.A. 80.7 23.9 N.A. 69.8 25.2 N.A. 48.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 40.1 38.9 N.A. N.A. 89.2 43.9 N.A. 84 40.1 N.A. 63.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 0 N.A. N.A. 86.6 6.6 N.A. 86.6 0 N.A. 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 13.3 N.A. N.A. 86.6 13.3 N.A. 86.6 6.6 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 38 0 0 0 13 0 0 0 0 25 0 % A
% Cys: 0 0 0 0 38 0 0 0 0 0 38 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % D
% Glu: 0 25 0 13 0 13 0 0 0 0 38 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 38 0 0 0 0 13 % F
% Gly: 0 0 0 0 0 25 0 0 0 0 13 0 0 0 0 % G
% His: 13 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % H
% Ile: 38 0 0 0 0 38 0 0 0 0 0 0 0 13 0 % I
% Lys: 0 38 38 25 0 0 0 13 13 0 0 38 13 13 38 % K
% Leu: 0 0 13 38 13 0 13 0 0 50 13 0 38 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 38 % N
% Pro: 0 0 0 0 0 0 38 0 0 0 0 0 38 0 0 % P
% Gln: 0 13 0 13 0 0 0 25 0 0 0 0 0 0 0 % Q
% Arg: 38 0 38 0 0 25 13 13 38 13 0 13 0 38 0 % R
% Ser: 0 13 13 0 0 0 25 38 0 0 0 0 0 0 13 % S
% Thr: 13 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % T
% Val: 0 0 0 0 0 0 0 0 38 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 13 0 0 0 0 0 0 38 0 0 0 % W
% Tyr: 0 13 0 13 0 0 0 0 0 0 0 13 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _