KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLR7
All Species:
11.52
Human Site:
S609
Identified Species:
36.19
UniProt:
Q9NYK1
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYK1
NP_057646.1
1049
120922
S609
M
M
N
D
N
D
I
S
S
S
T
S
R
T
M
Chimpanzee
Pan troglodytes
B3Y613
784
89806
Q390
E
D
A
W
P
S
L
Q
T
L
I
L
R
Q
N
Rhesus Macaque
Macaca mulatta
B3Y618
784
90053
Q390
E
D
A
W
P
S
L
Q
T
L
I
L
R
Q
N
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P58681
1050
121818
S610
M
M
N
D
N
D
I
S
T
S
A
S
R
T
M
Rat
Rattus norvegicus
Q9QX05
835
96053
F441
K
V
T
E
F
S
V
F
L
S
L
E
K
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515229
1059
121608
S619
I
M
N
G
N
E
I
S
T
S
T
S
M
V
M
Chicken
Gallus gallus
Q9DD78
793
90748
Q399
E
D
A
W
P
S
L
Q
T
L
N
L
S
K
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665957
1231
140895
S793
I
M
N
D
N
Q
I
S
T
S
T
N
T
E
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.6
23.6
N.A.
N.A.
80.7
23.9
N.A.
69.8
25.2
N.A.
48.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
40.1
38.9
N.A.
N.A.
89.2
43.9
N.A.
84
40.1
N.A.
63.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
N.A.
N.A.
86.6
6.6
N.A.
60
0
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
20
N.A.
N.A.
93.3
40
N.A.
80
13.3
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
38
0
0
0
0
0
0
0
13
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
38
0
38
0
25
0
0
0
0
0
0
0
0
0
% D
% Glu:
38
0
0
13
0
13
0
0
0
0
0
13
0
13
0
% E
% Phe:
0
0
0
0
13
0
0
13
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
25
0
0
0
0
0
50
0
0
0
25
0
0
0
0
% I
% Lys:
13
0
0
0
0
0
0
0
0
0
0
0
13
13
0
% K
% Leu:
0
0
0
0
0
0
38
0
13
38
13
38
0
13
13
% L
% Met:
25
50
0
0
0
0
0
0
0
0
0
0
13
0
50
% M
% Asn:
0
0
50
0
50
0
0
0
0
0
13
13
0
0
38
% N
% Pro:
0
0
0
0
38
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
13
0
38
0
0
0
0
0
25
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% R
% Ser:
0
0
0
0
0
50
0
50
13
63
0
38
13
0
0
% S
% Thr:
0
0
13
0
0
0
0
0
75
0
38
0
13
25
0
% T
% Val:
0
13
0
0
0
0
13
0
0
0
0
0
0
13
0
% V
% Trp:
0
0
0
38
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _