Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FKBP11 All Species: 18.18
Human Site: S127 Identified Species: 28.57
UniProt: Q9NYL4 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYL4 NP_001137253.1 201 22180 S127 G K R G F P P S V P A D A V V
Chimpanzee Pan troglodytes XP_001159891 204 22544 S130 G K R G F P P S V P A D A V V
Rhesus Macaque Macaca mulatta XP_001104575 204 22475 S130 G K R G F P P S V P A D A V V
Dog Lupus familis XP_851205 102 11532 E40 A V L Q F D V E L I A L I R A
Cat Felis silvestris
Mouse Mus musculus Q9D1M7 201 22119 S127 G K R G Y P P S I P A D A V V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516530 87 9430 T25 A D G R V I D T S L T R D P L
Chicken Gallus gallus
Frog Xenopus laevis NP_001087265 171 18950 L109 K V V I P P H L A Y G K K G Y
Zebra Danio Brachydanio rerio NP_001012249 192 20946 T121 G K R G Y P P T I P G D S T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_502056 139 15453 G77 E E F T F T L G Q G N V I K G
Sea Urchin Strong. purpuratus XP_001177639 192 21433 I124 G K K G S G P I P P D S T L V
Poplar Tree Populus trichocarpa XP_002301808 153 16028 W91 S G Q V I K G W D Q G L L G A
Maize Zea mays NP_001148416 148 15769 V86 F E L G T G Q V I K G W D Q G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38936 163 17640 V101 Q G L L G A C V G E K R K L K
Baker's Yeast Sacchar. cerevisiae P32472 135 14468 F73 S R G S P I A F E L G V G R V
Red Bread Mold Neurospora crassa P20080 120 13018 V57 G E P L N F T V G Q G Q V I K
Conservation
Percent
Protein Identity: 100 98.5 96 47.2 N.A. 90.5 N.A. N.A. 35.3 N.A. 45.2 50.7 N.A. N.A. N.A. 31.3 32.3
Protein Similarity: 100 98.5 97 50.2 N.A. 94 N.A. N.A. 40.2 N.A. 59.2 70.6 N.A. N.A. N.A. 47.2 56.2
P-Site Identity: 100 100 100 13.3 N.A. 86.6 N.A. N.A. 0 N.A. 6.6 53.3 N.A. N.A. N.A. 6.6 40
P-Site Similarity: 100 100 100 20 N.A. 100 N.A. N.A. 13.3 N.A. 6.6 86.6 N.A. N.A. N.A. 13.3 53.3
Percent
Protein Identity: 32.3 32.3 N.A. 30.3 26.8 26.8
Protein Similarity: 45.7 44.7 N.A. 44.7 44.2 36.3
P-Site Identity: 0 6.6 N.A. 0 6.6 6.6
P-Site Similarity: 6.6 20 N.A. 6.6 13.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 0 0 0 7 7 0 7 0 34 0 27 0 14 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 7 7 0 7 0 7 34 14 0 0 % D
% Glu: 7 20 0 0 0 0 0 7 7 7 0 0 0 0 0 % E
% Phe: 7 0 7 0 34 7 0 7 0 0 0 0 0 0 0 % F
% Gly: 47 14 14 47 7 14 7 7 14 7 40 0 7 14 14 % G
% His: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 7 14 0 7 20 7 0 0 14 7 0 % I
% Lys: 7 40 7 0 0 7 0 0 0 7 7 7 14 7 14 % K
% Leu: 0 0 20 14 0 0 7 7 7 14 0 14 7 14 14 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 0 0 0 7 0 0 0 0 % N
% Pro: 0 0 7 0 14 40 40 0 7 40 0 0 0 7 0 % P
% Gln: 7 0 7 7 0 0 7 0 7 14 0 7 0 7 0 % Q
% Arg: 0 7 34 7 0 0 0 0 0 0 0 14 0 14 0 % R
% Ser: 14 0 0 7 7 0 0 27 7 0 0 7 7 0 0 % S
% Thr: 0 0 0 7 7 7 7 14 0 0 7 0 7 7 0 % T
% Val: 0 14 7 7 7 0 7 20 20 0 0 14 7 27 40 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % W
% Tyr: 0 0 0 0 14 0 0 0 0 7 0 0 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _