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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FKBP11 All Species: 14.55
Human Site: S77 Identified Species: 22.86
UniProt: Q9NYL4 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYL4 NP_001137253.1 201 22180 S77 D G R I I D T S L T R D P L V
Chimpanzee Pan troglodytes XP_001159891 204 22544 S80 D G R I I D T S L T R D P L V
Rhesus Macaque Macaca mulatta XP_001104575 204 22475 S80 D G R I I D T S L T R D P L V
Dog Lupus familis XP_851205 102 11532
Cat Felis silvestris
Mouse Mus musculus Q9D1M7 201 22119 S77 D G R I I D T S L T R D P L V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516530 87 9430
Chicken Gallus gallus
Frog Xenopus laevis NP_001087265 171 18950 I65 G R L E D G R I I D S S L S R
Zebra Danio Brachydanio rerio NP_001012249 192 20946 P76 D T S L S R E P L V V E L G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_502056 139 15453 K33 K L Q I G V K K R A E N C V Q
Sea Urchin Strong. purpuratus XP_001177639 192 21433 R77 D S S R Q D N R E P I D F K L
Poplar Tree Populus trichocarpa XP_002301808 153 16028 Q47 K P E T C E V Q A H K G D S I
Maize Zea mays NP_001148416 148 15769 S42 G V K Y K P E S C S I Q A H K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38936 163 17640 V57 H K G D T I K V H Y R G K L T
Baker's Yeast Sacchar. cerevisiae P32472 135 14468 K29 D L E I G I I K R I P V E D C
Red Bread Mold Neurospora crassa P20080 120 13018 V13 L D G L Q I E V Q Q E G Q G T
Conservation
Percent
Protein Identity: 100 98.5 96 47.2 N.A. 90.5 N.A. N.A. 35.3 N.A. 45.2 50.7 N.A. N.A. N.A. 31.3 32.3
Protein Similarity: 100 98.5 97 50.2 N.A. 94 N.A. N.A. 40.2 N.A. 59.2 70.6 N.A. N.A. N.A. 47.2 56.2
P-Site Identity: 100 100 100 0 N.A. 100 N.A. N.A. 0 N.A. 0 13.3 N.A. N.A. N.A. 6.6 20
P-Site Similarity: 100 100 100 0 N.A. 100 N.A. N.A. 0 N.A. 6.6 26.6 N.A. N.A. N.A. 26.6 26.6
Percent
Protein Identity: 32.3 32.3 N.A. 30.3 26.8 26.8
Protein Similarity: 45.7 44.7 N.A. 44.7 44.2 36.3
P-Site Identity: 0 6.6 N.A. 13.3 13.3 0
P-Site Similarity: 20 20 N.A. 13.3 13.3 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 7 7 0 0 7 0 0 % A
% Cys: 0 0 0 0 7 0 0 0 7 0 0 0 7 0 7 % C
% Asp: 47 7 0 7 7 34 0 0 0 7 0 34 7 7 0 % D
% Glu: 0 0 14 7 0 7 20 0 7 0 14 7 7 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % F
% Gly: 14 27 14 0 14 7 0 0 0 0 0 20 0 14 0 % G
% His: 7 0 0 0 0 0 0 0 7 7 0 0 0 7 0 % H
% Ile: 0 0 0 40 27 20 7 7 7 7 14 0 0 0 7 % I
% Lys: 14 7 7 0 7 0 14 14 0 0 7 0 7 7 14 % K
% Leu: 7 14 7 14 0 0 0 0 34 0 0 0 14 34 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 7 0 0 0 0 7 0 0 0 % N
% Pro: 0 7 0 0 0 7 0 7 0 7 7 0 27 0 0 % P
% Gln: 0 0 7 0 14 0 0 7 7 7 0 7 7 0 7 % Q
% Arg: 0 7 27 7 0 7 7 7 14 0 34 0 0 0 7 % R
% Ser: 0 7 14 0 7 0 0 34 0 7 7 7 0 14 0 % S
% Thr: 0 7 0 7 7 0 27 0 0 27 0 0 0 0 14 % T
% Val: 0 7 0 0 0 7 7 14 0 7 7 7 0 7 27 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _