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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FKBP11 All Species: 22.42
Human Site: Y119 Identified Species: 35.24
UniProt: Q9NYL4 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYL4 NP_001137253.1 201 22180 Y119 I I P S H L A Y G K R G F P P
Chimpanzee Pan troglodytes XP_001159891 204 22544 Y122 I I P S H L A Y G K R G F P P
Rhesus Macaque Macaca mulatta XP_001104575 204 22475 Y122 I I P S H L A Y G K R G F P P
Dog Lupus familis XP_851205 102 11532 D32 F P P S I P A D A V L Q F D V
Cat Felis silvestris
Mouse Mus musculus Q9D1M7 201 22119 Y119 V I P S H L A Y G K R G Y P P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516530 87 9430 L17 I S K G N G S L A D G R V I D
Chicken Gallus gallus
Frog Xenopus laevis NP_001087265 171 18950 R101 G M C V G E K R K V V I P P H
Zebra Danio Brachydanio rerio NP_001012249 192 20946 Y113 M I P A H L A Y G K R G Y P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_502056 139 15453 N69 F D S S R T R N E E F T F T L
Sea Urchin Strong. purpuratus XP_001177639 192 21433 Y116 I I P P H L G Y G K K G S G P
Poplar Tree Populus trichocarpa XP_002301808 153 16028 G83 D P I G F E L G S G Q V I K G
Maize Zea mays NP_001148416 148 15769 E78 Y E R G D P I E F E L G T G Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38936 163 17640 D93 G Q V I K G W D Q G L L G A C
Baker's Yeast Sacchar. cerevisiae P32472 135 14468 Y65 G T V F D S S Y S R G S P I A
Red Bread Mold Neurospora crassa P20080 120 13018 R49 K F D A S Y D R G E P L N F T
Conservation
Percent
Protein Identity: 100 98.5 96 47.2 N.A. 90.5 N.A. N.A. 35.3 N.A. 45.2 50.7 N.A. N.A. N.A. 31.3 32.3
Protein Similarity: 100 98.5 97 50.2 N.A. 94 N.A. N.A. 40.2 N.A. 59.2 70.6 N.A. N.A. N.A. 47.2 56.2
P-Site Identity: 100 100 100 26.6 N.A. 86.6 N.A. N.A. 6.6 N.A. 6.6 80 N.A. N.A. N.A. 13.3 66.6
P-Site Similarity: 100 100 100 26.6 N.A. 100 N.A. N.A. 20 N.A. 13.3 100 N.A. N.A. N.A. 20 73.3
Percent
Protein Identity: 32.3 32.3 N.A. 30.3 26.8 26.8
Protein Similarity: 45.7 44.7 N.A. 44.7 44.2 36.3
P-Site Identity: 0 6.6 N.A. 0 6.6 6.6
P-Site Similarity: 6.6 13.3 N.A. 0 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 14 0 0 40 0 14 0 0 0 0 7 7 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 7 % C
% Asp: 7 7 7 0 14 0 7 14 0 7 0 0 0 7 7 % D
% Glu: 0 7 0 0 0 14 0 7 7 20 0 0 0 0 0 % E
% Phe: 14 7 0 7 7 0 0 0 7 0 7 0 34 7 0 % F
% Gly: 20 0 0 20 7 14 7 7 47 14 14 47 7 14 7 % G
% His: 0 0 0 0 40 0 0 0 0 0 0 0 0 0 7 % H
% Ile: 34 40 7 7 7 0 7 0 0 0 0 7 7 14 0 % I
% Lys: 7 0 7 0 7 0 7 0 7 40 7 0 0 7 0 % K
% Leu: 0 0 0 0 0 40 7 7 0 0 20 14 0 0 7 % L
% Met: 7 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 7 0 0 0 0 7 0 0 % N
% Pro: 0 14 47 7 0 14 0 0 0 0 7 0 14 40 40 % P
% Gln: 0 7 0 0 0 0 0 0 7 0 7 7 0 0 7 % Q
% Arg: 0 0 7 0 7 0 7 14 0 7 34 7 0 0 0 % R
% Ser: 0 7 7 40 7 7 14 0 14 0 0 7 7 0 0 % S
% Thr: 0 7 0 0 0 7 0 0 0 0 0 7 7 7 7 % T
% Val: 7 0 14 7 0 0 0 0 0 14 7 7 7 0 7 % V
% Trp: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 7 0 47 0 0 0 0 14 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _