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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FKBP11 All Species: 14.85
Human Site: Y177 Identified Species: 23.33
UniProt: Q9NYL4 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYL4 NP_001137253.1 201 22180 Y177 G L I G Y H L Y R K A N R P K
Chimpanzee Pan troglodytes XP_001159891 204 22544 Y180 G L I G Y H L Y R K A N R P K
Rhesus Macaque Macaca mulatta XP_001104575 204 22475 Y180 G L I G Y H L Y R K A N R P K
Dog Lupus familis XP_851205 102 11532 K79 L I G Y H L Y K K A S R P K V
Cat Felis silvestris
Mouse Mus musculus Q9D1M7 201 22119 Y177 G L I G Y H L Y R K A S R P K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516530 87 9430 P64 K R R A T I P P H L A Y G K R
Chicken Gallus gallus
Frog Xenopus laevis NP_001087265 171 18950 V148 W Q T I V N D V F P L L H W F
Zebra Danio Brachydanio rerio NP_001012249 192 20946 G167 P T L L G L V G L Y L Y N K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_502056 139 15453 K116 G E R G A P P K I P G N S V L
Sea Urchin Strong. purpuratus XP_001177639 192 21433 Y169 I V I L L L Y Y M W E K S A K
Poplar Tree Populus trichocarpa XP_002301808 153 16028 I130 I P G G A T L I F D T E L V E
Maize Zea mays NP_001148416 148 15769 G125 S P P T I P G G A T L I F D T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38936 163 17640 N140 D T E L I A V N E K P A G G E
Baker's Yeast Sacchar. cerevisiae P32472 135 14468 V112 L A Y G E R G V P G V I P P S
Red Bread Mold Neurospora crassa P20080 120 13018 I97 G N R A V G G I I P A N S T L
Conservation
Percent
Protein Identity: 100 98.5 96 47.2 N.A. 90.5 N.A. N.A. 35.3 N.A. 45.2 50.7 N.A. N.A. N.A. 31.3 32.3
Protein Similarity: 100 98.5 97 50.2 N.A. 94 N.A. N.A. 40.2 N.A. 59.2 70.6 N.A. N.A. N.A. 47.2 56.2
P-Site Identity: 100 100 100 0 N.A. 93.3 N.A. N.A. 6.6 N.A. 0 0 N.A. N.A. N.A. 20 20
P-Site Similarity: 100 100 100 26.6 N.A. 100 N.A. N.A. 13.3 N.A. 6.6 13.3 N.A. N.A. N.A. 20 26.6
Percent
Protein Identity: 32.3 32.3 N.A. 30.3 26.8 26.8
Protein Similarity: 45.7 44.7 N.A. 44.7 44.2 36.3
P-Site Identity: 13.3 0 N.A. 6.6 13.3 20
P-Site Similarity: 20 0 N.A. 20 13.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 14 14 7 0 0 7 7 40 7 0 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 7 0 0 7 0 0 0 7 0 % D
% Glu: 0 7 7 0 7 0 0 0 7 0 7 7 0 0 14 % E
% Phe: 0 0 0 0 0 0 0 0 14 0 0 0 7 0 7 % F
% Gly: 40 0 14 47 7 7 20 14 0 7 7 0 14 7 0 % G
% His: 0 0 0 0 7 27 0 0 7 0 0 0 7 0 0 % H
% Ile: 14 7 34 7 14 7 0 14 14 0 0 14 0 0 0 % I
% Lys: 7 0 0 0 0 0 0 14 7 34 0 7 0 20 34 % K
% Leu: 14 27 7 20 7 20 34 0 7 7 20 7 7 0 14 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 7 0 7 0 0 0 34 7 0 0 % N
% Pro: 7 14 7 0 0 14 14 7 7 20 7 0 14 34 0 % P
% Gln: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 7 20 0 0 7 0 0 27 0 0 7 27 0 7 % R
% Ser: 7 0 0 0 0 0 0 0 0 0 7 7 20 0 7 % S
% Thr: 0 14 7 7 7 7 0 0 0 7 7 0 0 7 7 % T
% Val: 0 7 0 0 14 0 14 14 0 0 7 0 0 14 7 % V
% Trp: 7 0 0 0 0 0 0 0 0 7 0 0 0 7 0 % W
% Tyr: 0 0 7 7 27 0 14 34 0 7 0 14 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _