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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP39A1
All Species:
6.67
Human Site:
S181
Identified Species:
13.33
UniProt:
Q9NYL5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYL5
NP_057677.2
469
54116
S181
L
F
N
K
S
L
F
S
T
N
K
K
K
I
K
Chimpanzee
Pan troglodytes
XP_518518
469
54055
S181
L
F
N
K
S
L
F
S
T
N
K
K
K
I
K
Rhesus Macaque
Macaca mulatta
XP_001102611
469
54028
P181
L
F
N
K
S
W
F
P
T
N
K
K
K
I
K
Dog
Lupus familis
XP_538946
469
54328
P181
L
F
K
K
G
L
F
P
R
N
E
G
K
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKJ9
470
53556
L184
L
F
K
K
G
L
F
L
T
D
K
R
T
I
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511640
415
47952
E144
E
Q
F
R
I
Y
D
E
G
F
E
F
G
S
Q
Chicken
Gallus gallus
XP_420063
419
47287
H149
E
L
H
E
H
M
A
H
L
G
T
E
G
T
G
Frog
Xenopus laevis
NP_001083508
504
57241
L215
K
N
L
L
K
G
G
L
L
N
P
L
I
I
L
Zebra Danio
Brachydanio rerio
NP_001025360
464
52846
P181
L
L
G
R
C
N
S
P
S
S
A
L
S
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789944
362
41142
V99
E
N
R
F
G
P
F
V
T
N
A
K
K
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LTL8
498
56791
L207
L
M
F
E
V
Q
K
L
G
A
L
S
N
S
D
Baker's Yeast
Sacchar. cerevisiae
P10614
530
60702
T207
Q
P
E
M
T
I
F
T
A
S
R
S
L
L
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97
84.8
N.A.
74.8
N.A.
N.A.
62
49.2
21.2
49.2
N.A.
N.A.
N.A.
N.A.
23.4
Protein Similarity:
100
99.5
97.8
92.3
N.A.
86.1
N.A.
N.A.
74.1
65
40.8
67.3
N.A.
N.A.
N.A.
N.A.
39.4
P-Site Identity:
100
100
86.6
53.3
N.A.
60
N.A.
N.A.
0
0
13.3
6.6
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
86.6
66.6
N.A.
73.3
N.A.
N.A.
20
26.6
13.3
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.6
20.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.3
40.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
9
9
17
0
0
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
9
% D
% Glu:
25
0
9
17
0
0
0
9
0
0
17
9
0
0
0
% E
% Phe:
0
42
17
9
0
0
59
0
0
9
0
9
0
0
0
% F
% Gly:
0
0
9
0
25
9
9
0
17
9
0
9
17
0
17
% G
% His:
0
0
9
0
9
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
9
0
0
0
0
0
0
9
50
9
% I
% Lys:
9
0
17
42
9
0
9
0
0
0
34
34
42
0
34
% K
% Leu:
59
17
9
9
0
34
0
25
17
0
9
17
9
9
9
% L
% Met:
0
9
0
9
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
25
0
0
9
0
0
0
50
0
0
9
0
0
% N
% Pro:
0
9
0
0
0
9
0
25
0
0
9
0
0
0
0
% P
% Gln:
9
9
0
0
0
9
0
0
0
0
0
0
0
0
17
% Q
% Arg:
0
0
9
17
0
0
0
0
9
0
9
9
0
17
9
% R
% Ser:
0
0
0
0
25
0
9
17
9
17
0
17
9
17
0
% S
% Thr:
0
0
0
0
9
0
0
9
42
0
9
0
9
9
0
% T
% Val:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _