KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP39A1
All Species:
16.97
Human Site:
S259
Identified Species:
33.94
UniProt:
Q9NYL5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYL5
NP_057677.2
469
54116
S259
D
I
V
E
T
E
T
S
K
E
N
S
P
N
Y
Chimpanzee
Pan troglodytes
XP_518518
469
54055
S259
D
I
V
E
T
E
T
S
K
E
N
S
P
N
Y
Rhesus Macaque
Macaca mulatta
XP_001102611
469
54028
S259
D
I
V
E
T
E
T
S
K
E
N
S
P
N
Y
Dog
Lupus familis
XP_538946
469
54328
K259
D
I
V
E
M
E
R
K
E
E
K
S
P
N
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKJ9
470
53556
T260
L
E
V
V
E
T
E
T
R
Q
Y
S
P
N
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511640
415
47952
W218
S
Y
A
V
L
L
L
W
A
S
Q
S
N
A
V
Chicken
Gallus gallus
XP_420063
419
47287
W222
N
Y
G
L
L
M
L
W
A
S
Q
A
N
A
V
Frog
Xenopus laevis
NP_001083508
504
57241
L293
S
G
N
Q
H
K
A
L
T
D
V
E
I
M
A
Zebra Danio
Brachydanio rerio
NP_001025360
464
52846
S255
Q
H
L
A
A
S
I
S
E
Q
Y
L
P
N
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789944
362
41142
Y172
L
I
F
F
L
A
G
Y
E
T
T
N
T
T
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LTL8
498
56791
T287
Q
G
D
S
F
K
L
T
I
D
N
L
K
G
I
Baker's Yeast
Sacchar. cerevisiae
P10614
530
60702
T300
Y
K
D
G
V
K
M
T
D
Q
E
I
A
N
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97
84.8
N.A.
74.8
N.A.
N.A.
62
49.2
21.2
49.2
N.A.
N.A.
N.A.
N.A.
23.4
Protein Similarity:
100
99.5
97.8
92.3
N.A.
86.1
N.A.
N.A.
74.1
65
40.8
67.3
N.A.
N.A.
N.A.
N.A.
39.4
P-Site Identity:
100
100
100
66.6
N.A.
33.3
N.A.
N.A.
6.6
0
0
26.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
73.3
N.A.
53.3
N.A.
N.A.
6.6
13.3
20
46.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.6
20.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.3
40.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
9
9
9
0
17
0
0
9
9
17
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
34
0
17
0
0
0
0
0
9
17
0
0
0
0
0
% D
% Glu:
0
9
0
34
9
34
9
0
25
34
9
9
0
0
0
% E
% Phe:
0
0
9
9
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
17
9
9
0
0
9
0
0
0
0
0
0
9
0
% G
% His:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
42
0
0
0
0
9
0
9
0
0
9
9
0
9
% I
% Lys:
0
9
0
0
0
25
0
9
25
0
9
0
9
0
0
% K
% Leu:
17
0
9
9
25
9
25
9
0
0
0
17
0
0
9
% L
% Met:
0
0
0
0
9
9
9
0
0
0
0
0
0
9
0
% M
% Asn:
9
0
9
0
0
0
0
0
0
0
34
9
17
59
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% P
% Gln:
17
0
0
9
0
0
0
0
0
25
17
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% R
% Ser:
17
0
0
9
0
9
0
34
0
17
0
50
0
0
0
% S
% Thr:
0
0
0
0
25
9
25
25
9
9
9
0
9
9
0
% T
% Val:
0
0
42
17
9
0
0
0
0
0
9
0
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% W
% Tyr:
9
17
0
0
0
0
0
9
0
0
17
0
0
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _