Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYP39A1 All Species: 15.15
Human Site: T182 Identified Species: 30.3
UniProt: Q9NYL5 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYL5 NP_057677.2 469 54116 T182 F N K S L F S T N K K K I K E
Chimpanzee Pan troglodytes XP_518518 469 54055 T182 F N K S L F S T N K K K I K E
Rhesus Macaque Macaca mulatta XP_001102611 469 54028 T182 F N K S W F P T N K K K I K E
Dog Lupus familis XP_538946 469 54328 R182 F K K G L F P R N E G K I R E
Cat Felis silvestris
Mouse Mus musculus Q9JKJ9 470 53556 T185 F K K G L F L T D K R T I K E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511640 415 47952 G145 Q F R I Y D E G F E F G S Q M
Chicken Gallus gallus XP_420063 419 47287 L150 L H E H M A H L G T E G T G D
Frog Xenopus laevis NP_001083508 504 57241 L216 N L L K G G L L N P L I I L V
Zebra Danio Brachydanio rerio NP_001025360 464 52846 S182 L G R C N S P S S A L S R Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789944 362 41142 T100 N R F G P F V T N A K K R I D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LTL8 498 56791 G208 M F E V Q K L G A L S N S D L
Baker's Yeast Sacchar. cerevisiae P10614 530 60702 A208 P E M T I F T A S R S L L G K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 97 84.8 N.A. 74.8 N.A. N.A. 62 49.2 21.2 49.2 N.A. N.A. N.A. N.A. 23.4
Protein Similarity: 100 99.5 97.8 92.3 N.A. 86.1 N.A. N.A. 74.1 65 40.8 67.3 N.A. N.A. N.A. N.A. 39.4
P-Site Identity: 100 100 86.6 53.3 N.A. 60 N.A. N.A. 0 0 13.3 6.6 N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: 100 100 86.6 66.6 N.A. 73.3 N.A. N.A. 20 33.3 13.3 33.3 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. 21.6 20.9 N.A.
Protein Similarity: N.A. N.A. N.A. 44.3 40.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 0 9 9 17 0 0 0 0 0 % A
% Cys: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 0 0 9 0 0 0 0 9 17 % D
% Glu: 0 9 17 0 0 0 9 0 0 17 9 0 0 0 50 % E
% Phe: 42 17 9 0 0 59 0 0 9 0 9 0 0 0 0 % F
% Gly: 0 9 0 25 9 9 0 17 9 0 9 17 0 17 0 % G
% His: 0 9 0 9 0 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 9 0 0 0 0 0 0 9 50 9 0 % I
% Lys: 0 17 42 9 0 9 0 0 0 34 34 42 0 34 9 % K
% Leu: 17 9 9 0 34 0 25 17 0 9 17 9 9 9 9 % L
% Met: 9 0 9 0 9 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 17 25 0 0 9 0 0 0 50 0 0 9 0 0 0 % N
% Pro: 9 0 0 0 9 0 25 0 0 9 0 0 0 0 0 % P
% Gln: 9 0 0 0 9 0 0 0 0 0 0 0 0 17 0 % Q
% Arg: 0 9 17 0 0 0 0 9 0 9 9 0 17 9 0 % R
% Ser: 0 0 0 25 0 9 17 9 17 0 17 9 17 0 0 % S
% Thr: 0 0 0 9 0 0 9 42 0 9 0 9 9 0 0 % T
% Val: 0 0 0 9 0 0 9 0 0 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _