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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYP39A1 All Species: 22.73
Human Site: Y203 Identified Species: 45.45
UniProt: Q9NYL5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYL5 NP_057677.2 469 54116 Y203 V Y D E D F E Y G S Q L P E C
Chimpanzee Pan troglodytes XP_518518 469 54055 Y203 A Y D E D F E Y G S Q L P E C
Rhesus Macaque Macaca mulatta XP_001102611 469 54028 Y203 A Y D E D F E Y G S Q L P E C
Dog Lupus familis XP_538946 469 54328 Y203 A Y D E G F E Y G S Q M P E C
Cat Felis silvestris
Mouse Mus musculus Q9JKJ9 470 53556 Y206 T Y D E G F E Y G S Q L P E W
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511640 415 47952 W166 N W S K S K Q W F L R L F E K
Chicken Gallus gallus XP_420063 419 47287 S171 H L L N W S K S K K W L L K L
Frog Xenopus laevis NP_001083508 504 57241 N237 R P I F E G L N I N F F P K N
Zebra Danio Brachydanio rerio NP_001025360 464 52846 Y203 T Y D E G F E Y G S Q L P E M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789944 362 41142 T121 D A Q E R D I T G N N K N K A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LTL8 498 56791 G229 W F V D F V S G H N K K L H K
Baker's Yeast Sacchar. cerevisiae P10614 530 60702 Y229 D T D F A Y L Y S D L D K G F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 97 84.8 N.A. 74.8 N.A. N.A. 62 49.2 21.2 49.2 N.A. N.A. N.A. N.A. 23.4
Protein Similarity: 100 99.5 97.8 92.3 N.A. 86.1 N.A. N.A. 74.1 65 40.8 67.3 N.A. N.A. N.A. N.A. 39.4
P-Site Identity: 100 93.3 93.3 80 N.A. 80 N.A. N.A. 13.3 6.6 6.6 80 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 93.3 93.3 86.6 N.A. 80 N.A. N.A. 46.6 20 26.6 80 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 21.6 20.9 N.A.
Protein Similarity: N.A. N.A. N.A. 44.3 40.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 9 0 0 9 0 0 0 0 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34 % C
% Asp: 17 0 59 9 25 9 0 0 0 9 0 9 0 0 0 % D
% Glu: 0 0 0 59 9 0 50 0 0 0 0 0 0 59 0 % E
% Phe: 0 9 0 17 9 50 0 0 9 0 9 9 9 0 9 % F
% Gly: 0 0 0 0 25 9 0 9 59 0 0 0 0 9 0 % G
% His: 9 0 0 0 0 0 0 0 9 0 0 0 0 9 0 % H
% Ile: 0 0 9 0 0 0 9 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 0 9 0 9 9 0 9 9 9 17 9 25 17 % K
% Leu: 0 9 9 0 0 0 17 0 0 9 9 59 17 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 9 % M
% Asn: 9 0 0 9 0 0 0 9 0 25 9 0 9 0 9 % N
% Pro: 0 9 0 0 0 0 0 0 0 0 0 0 59 0 0 % P
% Gln: 0 0 9 0 0 0 9 0 0 0 50 0 0 0 0 % Q
% Arg: 9 0 0 0 9 0 0 0 0 0 9 0 0 0 0 % R
% Ser: 0 0 9 0 9 9 9 9 9 50 0 0 0 0 0 % S
% Thr: 17 9 0 0 0 0 0 9 0 0 0 0 0 0 0 % T
% Val: 9 0 9 0 0 9 0 0 0 0 0 0 0 0 0 % V
% Trp: 9 9 0 0 9 0 0 9 0 0 9 0 0 0 9 % W
% Tyr: 0 50 0 0 0 9 0 59 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _