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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP39A1
All Species:
18.18
Human Site:
Y448
Identified Species:
36.36
UniProt:
Q9NYL5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYL5
NP_057677.2
469
54116
Y448
D
P
L
P
K
Q
S
Y
L
H
L
V
G
V
P
Chimpanzee
Pan troglodytes
XP_518518
469
54055
Y448
D
P
L
P
K
Q
S
Y
L
H
L
V
G
V
P
Rhesus Macaque
Macaca mulatta
XP_001102611
469
54028
S448
D
P
L
P
K
Q
S
S
L
H
L
V
G
V
P
Dog
Lupus familis
XP_538946
469
54328
F448
D
P
L
P
K
Q
S
F
L
H
L
V
G
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKJ9
470
53556
S449
D
P
L
P
K
Q
S
S
R
H
L
V
G
V
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511640
415
47952
S394
D
P
V
P
K
Q
S
S
R
H
L
I
G
T
Q
Chicken
Gallus gallus
XP_420063
419
47287
P398
D
A
V
P
K
E
S
P
L
H
L
V
G
T
Q
Frog
Xenopus laevis
NP_001083508
504
57241
E479
A
E
T
L
I
P
M
E
Y
S
T
I
G
V
L
Zebra Danio
Brachydanio rerio
NP_001025360
464
52846
P444
D
P
M
P
K
P
S
P
L
H
L
V
G
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789944
362
41142
T344
E
M
P
P
K
Q
A
T
N
G
F
L
S
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LTL8
498
56791
M476
E
E
D
K
D
L
D
M
E
E
A
G
D
V
T
Baker's Yeast
Sacchar. cerevisiae
P10614
530
60702
F506
K
T
V
P
P
P
D
F
T
S
M
V
T
L
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
97
84.8
N.A.
74.8
N.A.
N.A.
62
49.2
21.2
49.2
N.A.
N.A.
N.A.
N.A.
23.4
Protein Similarity:
100
99.5
97.8
92.3
N.A.
86.1
N.A.
N.A.
74.1
65
40.8
67.3
N.A.
N.A.
N.A.
N.A.
39.4
P-Site Identity:
100
100
93.3
86.6
N.A.
86.6
N.A.
N.A.
60
60
13.3
66.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
N.A.
N.A.
73.3
73.3
20
73.3
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.6
20.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.3
40.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
0
0
9
0
0
0
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
67
0
9
0
9
0
17
0
0
0
0
0
9
0
0
% D
% Glu:
17
17
0
0
0
9
0
9
9
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
17
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
9
0
9
75
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
67
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
0
0
17
0
0
0
% I
% Lys:
9
0
0
9
75
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
42
9
0
9
0
0
50
0
67
9
0
9
9
% L
% Met:
0
9
9
0
0
0
9
9
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
59
9
84
9
25
0
17
0
0
0
0
0
9
50
% P
% Gln:
0
0
0
0
0
59
0
0
0
0
0
0
0
0
34
% Q
% Arg:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
67
25
0
17
0
0
9
0
0
% S
% Thr:
0
9
9
0
0
0
0
9
9
0
9
0
9
25
9
% T
% Val:
0
0
25
0
0
0
0
0
0
0
0
67
0
59
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
17
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _