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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASL12
All Species:
28.48
Human Site:
S245
Identified Species:
48.21
UniProt:
Q9NYN1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYN1
NP_057647.1
266
29662
S245
A
K
L
V
T
V
K
S
S
R
A
Q
S
K
R
Chimpanzee
Pan troglodytes
XP_510479
266
29602
S245
A
K
L
V
T
V
K
S
S
R
A
Q
S
K
R
Rhesus Macaque
Macaca mulatta
XP_001108511
266
29588
S245
A
K
L
V
T
V
K
S
S
R
A
Q
S
K
R
Dog
Lupus familis
XP_544725
234
26404
S214
K
L
V
T
V
K
S
S
R
A
Q
S
K
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q08AT1
266
29536
S245
A
K
L
V
T
V
K
S
S
R
A
Q
S
K
R
Rat
Rattus norvegicus
Q5BJQ5
217
24743
R197
L
V
E
R
K
L
K
R
K
D
S
L
W
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518218
343
37266
S322
A
K
L
V
T
V
K
S
S
R
A
Q
S
K
R
Chicken
Gallus gallus
XP_413899
265
29618
S244
A
K
L
V
T
V
K
S
S
R
A
Q
S
K
R
Frog
Xenopus laevis
Q8AVS6
248
27595
M227
P
R
P
K
S
P
N
M
Q
D
L
K
R
R
F
Zebra Danio
Brachydanio rerio
Q7SZ59
255
28392
S234
A
K
L
V
T
V
K
S
S
R
A
Q
S
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08645
184
20845
I164
F
Y
D
L
V
R
Q
I
N
K
K
S
P
E
K
Honey Bee
Apis mellifera
XP_001119889
216
24087
L196
Q
S
L
L
D
R
M
L
G
S
K
A
T
R
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789332
282
32318
A258
T
K
M
T
A
P
K
A
P
R
V
V
P
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P22126
213
24008
K193
A
N
N
N
G
A
V
K
Q
M
D
V
G
D
E
Conservation
Percent
Protein Identity:
100
99.2
98.1
82.7
N.A.
93.6
30.8
N.A.
46.9
74
27.8
63.9
N.A.
24.8
33
N.A.
37.5
Protein Similarity:
100
100
99.2
84.9
N.A.
95.1
48.5
N.A.
57.1
84.9
46.9
77
N.A.
40.5
47.3
N.A.
54.9
P-Site Identity:
100
100
100
6.6
N.A.
100
13.3
N.A.
100
100
0
100
N.A.
0
6.6
N.A.
33.3
P-Site Similarity:
100
100
100
26.6
N.A.
100
33.3
N.A.
100
100
26.6
100
N.A.
40
26.6
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
27.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
48.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
58
0
0
0
8
8
0
8
0
8
50
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
0
0
0
0
15
8
0
0
8
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
8
0
0
0
8
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
8
58
0
8
8
8
65
8
8
8
15
8
8
65
22
% K
% Leu:
8
8
58
15
0
8
0
8
0
0
8
8
0
0
0
% L
% Met:
0
0
8
0
0
0
8
8
0
8
0
0
0
0
0
% M
% Asn:
0
8
8
8
0
0
8
0
8
0
0
0
0
0
0
% N
% Pro:
8
0
8
0
0
15
0
0
8
0
0
0
15
0
0
% P
% Gln:
8
0
0
0
0
0
8
0
15
0
8
50
0
0
0
% Q
% Arg:
0
8
0
8
0
15
0
8
8
58
0
0
8
22
58
% R
% Ser:
0
8
0
0
8
0
8
58
50
8
8
15
50
0
0
% S
% Thr:
8
0
0
15
50
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
8
8
50
15
50
8
0
0
0
8
15
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _