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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DONSON All Species: 15.76
Human Site: S28 Identified Species: 31.52
UniProt: Q9NYP3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYP3 NP_060083.1 566 62747 S28 L R R K R A R S R G A A A S P
Chimpanzee Pan troglodytes XP_001166225 566 62800 S28 L R R K R A R S R G A A A S P
Rhesus Macaque Macaca mulatta XP_001091031 564 62492 S28 L R R K R A R S R G A A A S P
Dog Lupus familis XP_535584 469 52593
Cat Felis silvestris
Mouse Mus musculus Q9QXP4 560 61969 S26 V R L R R K R S R D H G A A V
Rat Rattus norvegicus NP_001008288 488 54122 P16 S P S F K R P P E V V R L R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416713 559 61311 P26 L R L K R K R P R R S E P A A
Frog Xenopus laevis Q5U4U4 579 63766 S28 L S R R R S R S E A S K T G L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VNA8 568 63419 N28 Q R L K Q K K N K L A A R V S
Honey Bee Apis mellifera XP_393677 572 65097 A33 M K K R A L Q A R I N N T R I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001196037 573 63812 N26 M K V R L K R N R R S T S D L
Poplar Tree Populus trichocarpa XP_002323361 630 68308 S37 M V K R K T P S E L R G E Q L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96.4 71.5 N.A. 77.2 68.7 N.A. N.A. 62.3 59.7 N.A. N.A. 29.2 33.3 N.A. 32.2
Protein Similarity: 100 99.6 97.6 78.2 N.A. 84.8 74.5 N.A. N.A. 73.3 72 N.A. N.A. 45 53.1 N.A. 53.2
P-Site Identity: 100 100 100 0 N.A. 40 0 N.A. N.A. 40 33.3 N.A. N.A. 26.6 6.6 N.A. 13.3
P-Site Similarity: 100 100 100 0 N.A. 60 6.6 N.A. N.A. 53.3 53.3 N.A. N.A. 53.3 46.6 N.A. 53.3
Percent
Protein Identity: 20.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 36.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 25 0 9 0 9 34 34 34 17 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 9 0 0 0 9 0 % D
% Glu: 0 0 0 0 0 0 0 0 25 0 0 9 9 0 0 % E
% Phe: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 25 0 17 0 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 9 % I
% Lys: 0 17 17 42 17 34 9 0 9 0 0 9 0 0 0 % K
% Leu: 42 0 25 0 9 9 0 0 0 17 0 0 9 0 25 % L
% Met: 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 17 0 0 9 9 0 0 0 % N
% Pro: 0 9 0 0 0 0 17 17 0 0 0 0 9 0 25 % P
% Gln: 9 0 0 0 9 0 9 0 0 0 0 0 0 9 0 % Q
% Arg: 0 50 34 42 50 9 59 0 59 17 9 9 9 17 9 % R
% Ser: 9 9 9 0 0 9 0 50 0 0 25 0 9 25 9 % S
% Thr: 0 0 0 0 0 9 0 0 0 0 0 9 17 0 0 % T
% Val: 9 9 9 0 0 0 0 0 0 9 9 0 0 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _