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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DONSON All Species: 12.73
Human Site: S341 Identified Species: 25.45
UniProt: Q9NYP3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYP3 NP_060083.1 566 62747 S341 G H K K E T A S G T S L G Y G
Chimpanzee Pan troglodytes XP_001166225 566 62800 S341 G H K K E T A S G T S L G Y G
Rhesus Macaque Macaca mulatta XP_001091031 564 62492 S339 G Y K K E T A S G S S L G Y G
Dog Lupus familis XP_535584 469 52593 E259 E E Q V I S D E D E D E S F S
Cat Felis silvestris
Mouse Mus musculus Q9QXP4 560 61969 D336 G H K K K V R D P S L E S E E
Rat Rattus norvegicus NP_001008288 488 54122 C278 L C P Y F Y V C S Y Q F T V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416713 559 61311 S320 R S K K Q K N S E G N L E T E
Frog Xenopus laevis Q5U4U4 579 63766 P347 T G K K Q K K P E A A S Q G D
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VNA8 568 63419 S325 S G N A H D N S F N E E S T T
Honey Bee Apis mellifera XP_393677 572 65097 D334 K R R S D T I D S G C D T V D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001196037 573 63812 T345 P S P V E T E T T T A T A G Q
Poplar Tree Populus trichocarpa XP_002323361 630 68308 F397 L R E H D V C F S M P L C Y S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96.4 71.5 N.A. 77.2 68.7 N.A. N.A. 62.3 59.7 N.A. N.A. 29.2 33.3 N.A. 32.2
Protein Similarity: 100 99.6 97.6 78.2 N.A. 84.8 74.5 N.A. N.A. 73.3 72 N.A. N.A. 45 53.1 N.A. 53.2
P-Site Identity: 100 100 86.6 0 N.A. 26.6 0 N.A. N.A. 26.6 13.3 N.A. N.A. 6.6 6.6 N.A. 20
P-Site Similarity: 100 100 100 20 N.A. 40 0 N.A. N.A. 40 26.6 N.A. N.A. 6.6 20 N.A. 33.3
Percent
Protein Identity: 20.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 36.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 26.6 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 0 25 0 0 9 17 0 9 0 0 % A
% Cys: 0 9 0 0 0 0 9 9 0 0 9 0 9 0 0 % C
% Asp: 0 0 0 0 17 9 9 17 9 0 9 9 0 0 17 % D
% Glu: 9 9 9 0 34 0 9 9 17 9 9 25 9 9 17 % E
% Phe: 0 0 0 0 9 0 0 9 9 0 0 9 0 9 0 % F
% Gly: 34 17 0 0 0 0 0 0 25 17 0 0 25 17 25 % G
% His: 0 25 0 9 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 9 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 50 50 9 17 9 0 0 0 0 0 0 0 0 % K
% Leu: 17 0 0 0 0 0 0 0 0 0 9 42 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 0 17 0 0 9 9 0 0 0 0 % N
% Pro: 9 0 17 0 0 0 0 9 9 0 9 0 0 0 0 % P
% Gln: 0 0 9 0 17 0 0 0 0 0 9 0 9 0 9 % Q
% Arg: 9 17 9 0 0 0 9 0 0 0 0 0 0 0 0 % R
% Ser: 9 17 0 9 0 9 0 42 25 17 25 9 25 0 17 % S
% Thr: 9 0 0 0 0 42 0 9 9 25 0 9 17 17 9 % T
% Val: 0 0 0 17 0 17 9 0 0 0 0 0 0 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 9 0 9 0 0 0 9 0 0 0 34 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _