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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DONSON All Species: 23.64
Human Site: S381 Identified Species: 47.27
UniProt: Q9NYP3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYP3 NP_060083.1 566 62747 S381 I K K P D I L S I K L R K E K
Chimpanzee Pan troglodytes XP_001166225 566 62800 S381 I K K P D I L S I K L R K E K
Rhesus Macaque Macaca mulatta XP_001091031 564 62492 S379 I K K P D I L S I K L R K E K
Dog Lupus familis XP_535584 469 52593 M296 K E K H E V Q M D H R P E S V
Cat Felis silvestris
Mouse Mus musculus Q9QXP4 560 61969 S375 I K K P D V I S I K L R K E K
Rat Rattus norvegicus NP_001008288 488 54122 E315 L R E A M K S E G I E F S L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416713 559 61311 S373 V K K P D A I S I K L R K E K
Frog Xenopus laevis Q5U4U4 579 63766 S398 I K K P D S I S I K L R K E K
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VNA8 568 63419 E365 L E S L G V D E R E L R R I Q
Honey Bee Apis mellifera XP_393677 572 65097 N375 L E S L G V E N S E I R K I N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001196037 573 63812 R385 F P S L E P T R V K F Q T D Q
Poplar Tree Populus trichocarpa XP_002323361 630 68308 S435 T R R L S S L S D V D N S P Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96.4 71.5 N.A. 77.2 68.7 N.A. N.A. 62.3 59.7 N.A. N.A. 29.2 33.3 N.A. 32.2
Protein Similarity: 100 99.6 97.6 78.2 N.A. 84.8 74.5 N.A. N.A. 73.3 72 N.A. N.A. 45 53.1 N.A. 53.2
P-Site Identity: 100 100 100 6.6 N.A. 86.6 0 N.A. N.A. 80 86.6 N.A. N.A. 13.3 13.3 N.A. 6.6
P-Site Similarity: 100 100 100 33.3 N.A. 100 20 N.A. N.A. 93.3 93.3 N.A. N.A. 53.3 53.3 N.A. 40
Percent
Protein Identity: 20.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 36.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 33.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 50 0 9 0 17 0 9 0 0 9 0 % D
% Glu: 0 25 9 0 17 0 9 17 0 17 9 0 9 50 0 % E
% Phe: 9 0 0 0 0 0 0 0 0 0 9 9 0 0 0 % F
% Gly: 0 0 0 0 17 0 0 0 9 0 0 0 0 0 0 % G
% His: 0 0 0 9 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 42 0 0 0 0 25 25 0 50 9 9 0 0 17 0 % I
% Lys: 9 50 59 0 0 9 0 0 0 59 0 0 59 0 50 % K
% Leu: 25 0 0 34 0 0 34 0 0 0 59 0 0 9 0 % L
% Met: 0 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 0 0 9 0 0 9 % N
% Pro: 0 9 0 50 0 9 0 0 0 0 0 9 0 9 9 % P
% Gln: 0 0 0 0 0 0 9 0 0 0 0 9 0 0 25 % Q
% Arg: 0 17 9 0 0 0 0 9 9 0 9 67 9 0 0 % R
% Ser: 0 0 25 0 9 17 9 59 9 0 0 0 17 9 0 % S
% Thr: 9 0 0 0 0 0 9 0 0 0 0 0 9 0 0 % T
% Val: 9 0 0 0 0 34 0 0 9 9 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _