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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DONSON All Species: 13.33
Human Site: T339 Identified Species: 26.67
UniProt: Q9NYP3 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYP3 NP_060083.1 566 62747 T339 E S G H K K E T A S G T S L G
Chimpanzee Pan troglodytes XP_001166225 566 62800 T339 E S G H K K E T A S G T S L G
Rhesus Macaque Macaca mulatta XP_001091031 564 62492 T337 E S G Y K K E T A S G S S L G
Dog Lupus familis XP_535584 469 52593 S257 H G E E Q V I S D E D E D E S
Cat Felis silvestris
Mouse Mus musculus Q9QXP4 560 61969 V334 E I G H K K K V R D P S L E S
Rat Rattus norvegicus NP_001008288 488 54122 Y276 T K L C P Y F Y V C S Y Q F T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416713 559 61311 K318 E S R S K K Q K N S E G N L E
Frog Xenopus laevis Q5U4U4 579 63766 K345 D D T G K K Q K K P E A A S Q
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VNA8 568 63419 D323 D N S G N A H D N S F N E E S
Honey Bee Apis mellifera XP_393677 572 65097 T332 D S K R R S D T I D S G C D T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001196037 573 63812 T343 E A P S P V E T E T T T A T A
Poplar Tree Populus trichocarpa XP_002323361 630 68308 V395 S L L R E H D V C F S M P L C
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96.4 71.5 N.A. 77.2 68.7 N.A. N.A. 62.3 59.7 N.A. N.A. 29.2 33.3 N.A. 32.2
Protein Similarity: 100 99.6 97.6 78.2 N.A. 84.8 74.5 N.A. N.A. 73.3 72 N.A. N.A. 45 53.1 N.A. 53.2
P-Site Identity: 100 100 86.6 0 N.A. 33.3 0 N.A. N.A. 40 13.3 N.A. N.A. 6.6 13.3 N.A. 26.6
P-Site Similarity: 100 100 100 13.3 N.A. 46.6 0 N.A. N.A. 53.3 33.3 N.A. N.A. 20 33.3 N.A. 46.6
Percent
Protein Identity: 20.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 36.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 20 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 9 0 0 25 0 0 9 17 0 9 % A
% Cys: 0 0 0 9 0 0 0 0 9 9 0 0 9 0 9 % C
% Asp: 25 9 0 0 0 0 17 9 9 17 9 0 9 9 0 % D
% Glu: 50 0 9 9 9 0 34 0 9 9 17 9 9 25 9 % E
% Phe: 0 0 0 0 0 0 9 0 0 9 9 0 0 9 0 % F
% Gly: 0 9 34 17 0 0 0 0 0 0 25 17 0 0 25 % G
% His: 9 0 0 25 0 9 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 0 9 0 9 0 0 0 0 0 0 % I
% Lys: 0 9 9 0 50 50 9 17 9 0 0 0 0 0 0 % K
% Leu: 0 9 17 0 0 0 0 0 0 0 0 0 9 42 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % M
% Asn: 0 9 0 0 9 0 0 0 17 0 0 9 9 0 0 % N
% Pro: 0 0 9 0 17 0 0 0 0 9 9 0 9 0 0 % P
% Gln: 0 0 0 0 9 0 17 0 0 0 0 0 9 0 9 % Q
% Arg: 0 0 9 17 9 0 0 0 9 0 0 0 0 0 0 % R
% Ser: 9 42 9 17 0 9 0 9 0 42 25 17 25 9 25 % S
% Thr: 9 0 9 0 0 0 0 42 0 9 9 25 0 9 17 % T
% Val: 0 0 0 0 0 17 0 17 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 9 0 9 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _