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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DONSON All Species: 18.18
Human Site: T473 Identified Species: 36.36
UniProt: Q9NYP3 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYP3 NP_060083.1 566 62747 T473 D Q F S L E I T G P I M P H S
Chimpanzee Pan troglodytes XP_001166225 566 62800 T473 D Q F S L E I T G P I M P H S
Rhesus Macaque Macaca mulatta XP_001091031 564 62492 T471 D Q F S L E I T G P I M P H S
Dog Lupus familis XP_535584 469 52593 H385 P I M P H S L H S V T M L L R
Cat Felis silvestris
Mouse Mus musculus Q9QXP4 560 61969 T467 D K F S L D I T G P V M P H A
Rat Rattus norvegicus NP_001008288 488 54122 L404 K G L N T F K L L N F L I N C
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416713 559 61311 V465 D I F S L E I V G P V L P H S
Frog Xenopus laevis Q5U4U4 579 63766 T490 D Q F S L E I T G P I M P H S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VNA8 568 63419 L466 I D I K G L I L P T F L P S V
Honey Bee Apis mellifera XP_393677 572 65097 L476 L E L K G P L L P H V L P S L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001196037 573 63812 V476 V E V S S L E V T G P I M P H
Poplar Tree Populus trichocarpa XP_002323361 630 68308 K534 L L S S I E I K D A Y I P S W
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96.4 71.5 N.A. 77.2 68.7 N.A. N.A. 62.3 59.7 N.A. N.A. 29.2 33.3 N.A. 32.2
Protein Similarity: 100 99.6 97.6 78.2 N.A. 84.8 74.5 N.A. N.A. 73.3 72 N.A. N.A. 45 53.1 N.A. 53.2
P-Site Identity: 100 100 100 6.6 N.A. 73.3 0 N.A. N.A. 73.3 100 N.A. N.A. 13.3 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 13.3 N.A. 100 20 N.A. N.A. 86.6 100 N.A. N.A. 20 33.3 N.A. 20
Percent
Protein Identity: 20.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 36.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 40 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 50 9 0 0 0 9 0 0 9 0 0 0 0 0 0 % D
% Glu: 0 17 0 0 0 50 9 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 50 0 0 9 0 0 0 0 17 0 0 0 0 % F
% Gly: 0 9 0 0 17 0 0 0 50 9 0 0 0 0 0 % G
% His: 0 0 0 0 9 0 0 9 0 9 0 0 0 50 9 % H
% Ile: 9 17 9 0 9 0 67 0 0 0 34 17 9 0 0 % I
% Lys: 9 9 0 17 0 0 9 9 0 0 0 0 0 0 0 % K
% Leu: 17 9 17 0 50 17 17 25 9 0 0 34 9 9 9 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 50 9 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 9 0 0 0 9 0 % N
% Pro: 9 0 0 9 0 9 0 0 17 50 9 0 75 9 0 % P
% Gln: 0 34 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % R
% Ser: 0 0 9 67 9 9 0 0 9 0 0 0 0 25 42 % S
% Thr: 0 0 0 0 9 0 0 42 9 9 9 0 0 0 0 % T
% Val: 9 0 9 0 0 0 0 17 0 9 25 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _