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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MIS18A
All Species:
14.55
Human Site:
S126
Identified Species:
45.71
UniProt:
Q9NYP9
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYP9
NP_061817.1
233
25863
S126
V
D
K
E
Q
K
L
S
K
R
E
K
E
N
G
Chimpanzee
Pan troglodytes
Q68UT5
232
25813
S125
V
D
K
E
Q
K
L
S
K
R
E
K
E
N
G
Rhesus Macaque
Macaca mulatta
XP_001097780
186
20635
K83
Q
K
L
S
K
R
E
K
E
N
G
C
I
L
E
Dog
Lupus familis
XP_852107
238
26528
S131
V
D
K
E
Q
I
L
S
K
R
K
N
E
N
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZJ6
204
22931
D101
P
K
L
S
K
C
R
D
E
D
G
C
I
L
E
Rat
Rattus norvegicus
B2RZC4
223
25198
S117
V
D
K
E
Q
K
L
S
K
C
R
D
E
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416702
204
22197
P101
E
Q
K
L
S
K
R
P
G
E
C
G
C
M
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002663634
223
24656
S115
V
G
K
E
P
F
V
S
G
T
R
K
E
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
60.5
78.1
N.A.
69
72
N.A.
N.A.
47.2
N.A.
33
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
67.3
82.3
N.A.
76.3
80.2
N.A.
N.A.
63.5
N.A.
52.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
80
N.A.
0
73.3
N.A.
N.A.
13.3
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
86.6
N.A.
13.3
80
N.A.
N.A.
13.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
13
0
0
0
13
13
25
13
0
0
% C
% Asp:
0
50
0
0
0
0
0
13
0
13
0
13
0
13
0
% D
% Glu:
13
0
0
63
0
0
13
0
25
13
25
0
63
0
25
% E
% Phe:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
13
0
0
0
0
0
0
25
0
25
13
0
0
63
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
13
0
0
0
0
0
0
25
0
0
% I
% Lys:
0
25
75
0
25
50
0
13
50
0
13
38
0
0
0
% K
% Leu:
0
0
25
13
0
0
50
0
0
0
0
0
0
38
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
13
0
13
0
38
0
% N
% Pro:
13
0
0
0
13
0
0
13
0
0
0
0
0
0
0
% P
% Gln:
13
13
0
0
50
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
13
25
0
0
38
25
0
0
0
0
% R
% Ser:
0
0
0
25
13
0
0
63
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% T
% Val:
63
0
0
0
0
0
13
0
0
0
0
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _