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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HAO2
All Species:
10.3
Human Site:
S184
Identified Species:
20.61
UniProt:
Q9NYQ3
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYQ3
NP_001005783.1
351
38839
S184
L
T
L
T
D
L
Q
S
P
K
K
G
N
A
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113689
351
38810
S184
L
T
L
T
D
L
Q
S
P
K
K
G
N
S
I
Dog
Lupus familis
XP_533023
353
39511
S186
L
L
L
K
D
L
R
S
T
K
E
R
N
P
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9NYQ2
353
38681
S186
I
K
L
K
D
L
R
S
P
G
E
S
K
S
G
Rat
Rattus norvegicus
Q07523
353
39183
A186
I
L
L
K
D
L
R
A
L
K
E
E
K
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514644
368
40523
G198
L
A
F
S
S
K
K
G
Y
G
D
K
S
G
L
Chicken
Gallus gallus
XP_416535
378
41978
F211
L
K
N
L
E
G
A
F
E
G
D
D
R
S
E
Frog
Xenopus laevis
NP_001086109
356
39447
E189
K
N
F
E
G
V
F
E
G
H
S
G
P
D
N
Zebra Danio
Brachydanio rerio
NP_956777
357
40150
E190
N
F
E
G
M
F
Q
E
Q
T
E
A
Q
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625149
367
40542
N196
K
L
S
T
K
I
N
N
A
E
S
G
S
G
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LRR9
367
40323
D192
G
L
D
L
G
K
M
D
E
A
N
D
S
G
L
Baker's Yeast
Sacchar. cerevisiae
P00175
591
65521
N391
P
K
A
M
K
K
T
N
V
E
E
S
Q
G
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.3
81.8
N.A.
71
73.6
N.A.
49.4
56.3
62
60.7
N.A.
N.A.
46
N.A.
N.A.
Protein Similarity:
100
N.A.
97.4
90.3
N.A.
84.9
83.5
N.A.
67.3
72.2
80
77.8
N.A.
N.A.
65.9
N.A.
N.A.
P-Site Identity:
100
N.A.
93.3
46.6
N.A.
33.3
26.6
N.A.
6.6
6.6
6.6
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
66.6
N.A.
60
53.3
N.A.
33.3
20
13.3
13.3
N.A.
N.A.
46.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.3
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.6
37.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
0
0
9
9
9
9
0
9
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
42
0
0
9
0
0
17
17
0
9
0
% D
% Glu:
0
0
9
9
9
0
0
17
17
17
42
9
0
9
17
% E
% Phe:
0
9
17
0
0
9
9
9
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
9
17
9
0
9
9
25
0
34
0
34
9
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
17
0
0
0
0
9
0
0
0
0
0
0
0
0
17
% I
% Lys:
17
25
0
25
17
25
9
0
0
34
17
9
17
0
0
% K
% Leu:
42
34
42
17
0
42
0
0
9
0
0
0
0
0
25
% L
% Met:
0
0
0
9
9
0
9
0
0
0
0
0
0
0
9
% M
% Asn:
9
9
9
0
0
0
9
17
0
0
9
0
25
0
9
% N
% Pro:
9
0
0
0
0
0
0
0
25
0
0
0
9
17
0
% P
% Gln:
0
0
0
0
0
0
25
0
9
0
0
0
17
0
0
% Q
% Arg:
0
0
0
0
0
0
25
0
0
0
0
9
9
0
0
% R
% Ser:
0
0
9
9
9
0
0
34
0
0
17
17
25
25
0
% S
% Thr:
0
17
0
25
0
0
9
0
9
9
0
0
0
0
9
% T
% Val:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _