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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HAO2
All Species:
34.85
Human Site:
Y275
Identified Species:
69.7
UniProt:
Q9NYQ3
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYQ3
NP_001005783.1
351
38839
Y275
V
K
G
K
I
E
V
Y
L
D
G
G
V
R
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113689
351
38810
Y275
V
K
G
K
I
E
V
Y
L
D
G
G
V
R
T
Dog
Lupus familis
XP_533023
353
39511
Y277
V
K
G
K
M
E
V
Y
L
D
G
G
I
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9NYQ2
353
38681
Y277
V
N
G
K
I
E
V
Y
M
D
G
G
V
R
T
Rat
Rattus norvegicus
Q07523
353
39183
Y277
V
K
G
K
I
E
V
Y
M
D
G
G
V
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514644
368
40523
F289
V
E
G
Q
V
E
V
F
L
D
G
G
V
R
K
Chicken
Gallus gallus
XP_416535
378
41978
Y302
V
R
D
R
V
E
V
Y
L
D
G
G
I
R
K
Frog
Xenopus laevis
NP_001086109
356
39447
Y280
V
Q
G
R
I
E
V
Y
L
D
G
G
I
R
T
Zebra Danio
Brachydanio rerio
NP_956777
357
40150
Y281
V
Q
G
R
V
E
V
Y
M
D
G
G
I
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625149
367
40542
Y287
V
N
G
K
L
E
I
Y
M
D
G
G
I
R
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LRR9
367
40323
F283
T
Q
G
R
I
P
V
F
L
D
G
G
V
R
R
Baker's Yeast
Sacchar. cerevisiae
P00175
591
65521
D482
L
E
Q
R
N
L
K
D
K
L
E
V
F
V
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.3
81.8
N.A.
71
73.6
N.A.
49.4
56.3
62
60.7
N.A.
N.A.
46
N.A.
N.A.
Protein Similarity:
100
N.A.
97.4
90.3
N.A.
84.9
83.5
N.A.
67.3
72.2
80
77.8
N.A.
N.A.
65.9
N.A.
N.A.
P-Site Identity:
100
N.A.
100
86.6
N.A.
86.6
93.3
N.A.
66.6
60
80
66.6
N.A.
N.A.
60
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
100
N.A.
93.3
86.6
100
100
N.A.
N.A.
86.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.3
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.6
37.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
9
0
92
0
0
0
0
9
% D
% Glu:
0
17
0
0
0
84
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
17
0
0
0
0
9
0
0
% F
% Gly:
0
0
84
0
0
0
0
0
0
0
92
92
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
50
0
9
0
0
0
0
0
42
0
0
% I
% Lys:
0
34
0
50
0
0
9
0
9
0
0
0
0
0
17
% K
% Leu:
9
0
0
0
9
9
0
0
59
9
0
0
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
34
0
0
0
0
0
0
% M
% Asn:
0
17
0
0
9
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
25
9
9
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
9
0
42
0
0
0
0
0
0
0
0
0
92
9
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
59
% T
% Val:
84
0
0
0
25
0
84
0
0
0
0
9
50
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _