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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAT2
All Species:
18.18
Human Site:
S4143
Identified Species:
33.33
UniProt:
Q9NYQ8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYQ8
NP_001438.1
4349
479392
S4143
K
Q
R
P
V
V
C
S
V
P
P
R
L
P
P
Chimpanzee
Pan troglodytes
XP_001168406
4349
479255
S4143
K
Q
R
P
V
V
C
S
V
P
P
R
L
P
P
Rhesus Macaque
Macaca mulatta
XP_001110265
4349
479328
S4143
K
Q
R
P
V
V
C
S
V
P
P
R
L
P
P
Dog
Lupus familis
XP_536461
4354
480494
S4148
K
Q
R
P
V
V
C
S
V
P
P
R
L
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNA6
4555
501992
N4218
L
R
A
G
D
G
R
N
V
Y
Q
E
V
G
P
Rat
Rattus norvegicus
O88277
4351
480635
S4145
K
Q
R
P
M
V
C
S
V
P
P
R
L
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508966
4273
469286
E4063
A
G
T
I
L
E
E
E
S
I
K
Q
C
C
S
Chicken
Gallus gallus
XP_414584
4382
482412
C4173
K
H
R
G
T
I
V
C
S
V
A
P
N
L
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920058
4342
480159
P4148
E
L
G
P
Q
V
G
P
R
P
Q
R
P
Q
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW71
4705
524557
A4378
Q
R
P
I
S
Y
T
A
V
P
N
D
N
L
V
Honey Bee
Apis mellifera
XP_394631
3607
400577
N3415
S
F
H
S
N
E
S
N
E
S
N
T
H
Q
L
Nematode Worm
Caenorhab. elegans
Q19319
4292
477180
V4087
N
T
R
V
L
V
P
V
V
P
P
P
L
P
P
Sea Urchin
Strong. purpuratus
XP_785422
3852
424350
L3660
W
V
Q
H
P
E
S
L
N
N
I
P
E
I
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.2
88.3
N.A.
41
81.7
N.A.
64.6
62.2
N.A.
46.8
N.A.
31.9
20.6
26.1
20.4
Protein Similarity:
100
99.5
98.5
93.7
N.A.
59.4
90
N.A.
77.1
76.2
N.A.
64.6
N.A.
50.1
37.8
46.1
37.7
P-Site Identity:
100
100
100
100
N.A.
13.3
93.3
N.A.
0
20
N.A.
26.6
N.A.
13.3
0
53.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
33.3
100
N.A.
13.3
26.6
N.A.
33.3
N.A.
33.3
6.6
60
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
8
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
39
8
0
0
0
0
8
8
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
8
0
0
0
0
24
8
8
8
0
0
8
8
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
16
0
8
8
0
0
0
0
0
0
8
8
% G
% His:
0
8
8
8
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
16
0
8
0
0
0
8
8
0
0
8
0
% I
% Lys:
47
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
8
8
0
0
16
0
0
8
0
0
0
0
47
16
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
0
16
8
8
16
0
16
0
0
% N
% Pro:
0
0
8
47
8
0
8
8
0
62
47
24
8
47
70
% P
% Gln:
8
39
8
0
8
0
0
0
0
0
16
8
0
16
0
% Q
% Arg:
0
16
54
0
0
0
8
0
8
0
0
47
0
0
0
% R
% Ser:
8
0
0
8
8
0
16
39
16
8
0
0
0
0
8
% S
% Thr:
0
8
8
0
8
0
8
0
0
0
0
8
0
0
0
% T
% Val:
0
8
0
8
31
54
8
8
62
8
0
0
8
0
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _