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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAT2 All Species: 18.48
Human Site: S4157 Identified Species: 33.89
UniProt: Q9NYQ8 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYQ8 NP_001438.1 4349 479392 S4157 P A A V P S H S D N E P V I K
Chimpanzee Pan troglodytes XP_001168406 4349 479255 S4157 P A A V P S H S D N E P V I K
Rhesus Macaque Macaca mulatta XP_001110265 4349 479328 S4157 P A A V P S H S D N E P V I K
Dog Lupus familis XP_536461 4354 480494 S4162 P A A A P S H S D N E S I I K
Cat Felis silvestris
Mouse Mus musculus Q8BNA6 4555 501992 P4232 P P Q V P V R P M A Y T P C F
Rat Rattus norvegicus O88277 4351 480635 P4159 P A A V S S H P G H E P I I K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508966 4273 469286 Q4077 S H E S D C S Q N P C L N D G
Chicken Gallus gallus XP_414584 4382 482412 S4187 P P A P P S N S D N E S F V K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001920058 4342 480159 A4162 G P V I C S V A P N L P P P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VW71 4705 524557 V4392 V L S N R N F V N N L D I L R
Honey Bee Apis mellifera XP_394631 3607 400577 V3429 L P S V H G S V D P A R D I E
Nematode Worm Caenorhab. elegans Q19319 4292 477180 S4101 P R G F R N D S S N F I S T S
Sea Urchin Strong. purpuratus XP_785422 3852 424350 S3674 P P R A P R D S P T N V S T T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.2 88.3 N.A. 41 81.7 N.A. 64.6 62.2 N.A. 46.8 N.A. 31.9 20.6 26.1 20.4
Protein Similarity: 100 99.5 98.5 93.7 N.A. 59.4 90 N.A. 77.1 76.2 N.A. 64.6 N.A. 50.1 37.8 46.1 37.7
P-Site Identity: 100 100 100 80 N.A. 20 66.6 N.A. 0 60 N.A. 20 N.A. 6.6 20 20 20
P-Site Similarity: 100 100 100 86.6 N.A. 20 80 N.A. 6.6 73.3 N.A. 33.3 N.A. 46.6 33.3 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 39 47 16 0 0 0 8 0 8 8 0 0 0 0 % A
% Cys: 0 0 0 0 8 8 0 0 0 0 8 0 0 8 0 % C
% Asp: 0 0 0 0 8 0 16 0 47 0 0 8 8 8 0 % D
% Glu: 0 0 8 0 0 0 0 0 0 0 47 0 0 0 8 % E
% Phe: 0 0 0 8 0 0 8 0 0 0 8 0 8 0 8 % F
% Gly: 8 0 8 0 0 8 0 0 8 0 0 0 0 0 8 % G
% His: 0 8 0 0 8 0 39 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 0 8 24 47 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47 % K
% Leu: 8 8 0 0 0 0 0 0 0 0 16 8 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 16 8 0 16 62 8 0 8 0 0 % N
% Pro: 70 39 0 8 54 0 0 16 16 16 0 39 16 8 8 % P
% Gln: 0 0 8 0 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 0 8 8 0 16 8 8 0 0 0 0 8 0 0 8 % R
% Ser: 8 0 16 8 8 54 16 54 8 0 0 16 16 0 8 % S
% Thr: 0 0 0 0 0 0 0 0 0 8 0 8 0 16 8 % T
% Val: 8 0 8 47 0 8 8 16 0 0 0 8 24 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _