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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAT2
All Species:
10.91
Human Site:
S4254
Identified Species:
20
UniProt:
Q9NYQ8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYQ8
NP_001438.1
4349
479392
S4254
N
L
E
D
L
M
P
S
R
P
P
S
P
R
E
Chimpanzee
Pan troglodytes
XP_001168406
4349
479255
S4254
N
L
E
D
L
M
P
S
R
P
P
S
P
R
E
Rhesus Macaque
Macaca mulatta
XP_001110265
4349
479328
S4254
N
L
E
D
L
M
P
S
R
P
P
S
P
R
E
Dog
Lupus familis
XP_536461
4354
480494
P4259
N
L
E
D
L
M
P
P
R
P
P
S
P
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNA6
4555
501992
P4420
S
R
D
Q
L
P
P
P
L
P
E
D
F
P
D
Rat
Rattus norvegicus
O88277
4351
480635
P4256
N
L
E
D
L
M
P
P
R
P
P
S
P
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508966
4273
469286
P4178
F
L
P
P
P
P
P
P
R
P
P
S
P
R
D
Chicken
Gallus gallus
XP_414584
4382
482412
L4286
S
N
Q
N
L
E
D
L
L
P
L
G
P
V
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920058
4342
480159
D4254
C
Y
S
N
Q
N
L
D
D
F
L
G
P
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW71
4705
524557
N4484
L
I
Q
V
E
M
P
N
V
C
H
S
S
S
A
Honey Bee
Apis mellifera
XP_394631
3607
400577
D3521
R
L
S
T
L
E
S
D
E
E
E
D
D
V
V
Nematode Worm
Caenorhab. elegans
Q19319
4292
477180
S4194
G
I
D
D
R
I
D
S
S
L
K
Y
S
R
A
Sea Urchin
Strong. purpuratus
XP_785422
3852
424350
D3766
S
T
S
T
V
P
P
D
Y
D
G
I
G
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.2
88.3
N.A.
41
81.7
N.A.
64.6
62.2
N.A.
46.8
N.A.
31.9
20.6
26.1
20.4
Protein Similarity:
100
99.5
98.5
93.7
N.A.
59.4
90
N.A.
77.1
76.2
N.A.
64.6
N.A.
50.1
37.8
46.1
37.7
P-Site Identity:
100
100
100
93.3
N.A.
20
93.3
N.A.
53.3
26.6
N.A.
6.6
N.A.
20
13.3
20
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
40
93.3
N.A.
60
46.6
N.A.
13.3
N.A.
40
13.3
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% A
% Cys:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
16
47
0
0
16
24
8
8
0
16
8
8
16
% D
% Glu:
0
0
39
0
8
16
0
0
8
8
16
0
0
0
47
% E
% Phe:
8
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
8
16
8
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
16
0
0
0
8
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
8
54
0
0
62
0
8
8
16
8
16
0
0
0
0
% L
% Met:
0
0
0
0
0
47
0
0
0
0
0
0
0
0
0
% M
% Asn:
39
8
0
16
0
8
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
8
8
24
70
31
0
62
47
0
62
8
0
% P
% Gln:
0
0
16
8
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
8
0
0
8
0
0
0
47
0
0
0
0
54
0
% R
% Ser:
24
0
24
0
0
0
8
31
8
0
0
54
16
8
8
% S
% Thr:
0
8
0
16
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
8
0
0
0
8
0
0
0
0
16
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _