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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAT2 All Species: 30.91
Human Site: S4303 Identified Species: 56.67
UniProt: Q9NYQ8 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYQ8 NP_001438.1 4349 479392 S4303 K G V G M R L S R A G P S Y A
Chimpanzee Pan troglodytes XP_001168406 4349 479255 S4303 K G V S M R L S R A G P S Y A
Rhesus Macaque Macaca mulatta XP_001110265 4349 479328 S4303 K G M S M R L S R A G P S Y A
Dog Lupus familis XP_536461 4354 480494 S4308 K G V S M R L S R A G P S Y A
Cat Felis silvestris
Mouse Mus musculus Q8BNA6 4555 501992 S4477 D L G G P S S S C D F S T F A
Rat Rattus norvegicus O88277 4351 480635 S4305 K G V S M R L S R A G P S Y A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508966 4273 469286 S4227 K R V S V R L S V A Q P S Y A
Chicken Gallus gallus XP_414584 4382 482412 S4335 K R V S M R L S V A Q P S Y A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001920058 4342 480159 S4302 K R L S V R L S V A Q P S Y A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VW71 4705 524557 S4533 P G A E I A D S S S L H S N D
Honey Bee Apis mellifera XP_394631 3607 400577 N3569 L L G G A T S N S D L S T N L
Nematode Worm Caenorhab. elegans Q19319 4292 477180 A4243 E K P P A I P A H A T P L E S
Sea Urchin Strong. purpuratus XP_785422 3852 424350 T3814 S M S M Y T S T N A S C S D V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.2 88.3 N.A. 41 81.7 N.A. 64.6 62.2 N.A. 46.8 N.A. 31.9 20.6 26.1 20.4
Protein Similarity: 100 99.5 98.5 93.7 N.A. 59.4 90 N.A. 77.1 76.2 N.A. 64.6 N.A. 50.1 37.8 46.1 37.7
P-Site Identity: 100 93.3 86.6 93.3 N.A. 20 93.3 N.A. 66.6 73.3 N.A. 60 N.A. 20 6.6 13.3 13.3
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 33.3 93.3 N.A. 73.3 73.3 N.A. 73.3 N.A. 33.3 20 33.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 16 8 0 8 0 77 0 0 0 0 70 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % C
% Asp: 8 0 0 0 0 0 8 0 0 16 0 0 0 8 8 % D
% Glu: 8 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % F
% Gly: 0 47 16 24 0 0 0 0 0 0 39 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 62 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 16 8 0 0 0 62 0 0 0 16 0 8 0 8 % L
% Met: 0 8 8 8 47 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 8 0 0 0 0 16 0 % N
% Pro: 8 0 8 8 8 0 8 0 0 0 0 70 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 24 0 0 0 0 % Q
% Arg: 0 24 0 0 0 62 0 0 39 0 0 0 0 0 0 % R
% Ser: 8 0 8 54 0 8 24 77 16 8 8 16 77 0 8 % S
% Thr: 0 0 0 0 0 16 0 8 0 0 8 0 16 0 0 % T
% Val: 0 0 47 0 16 0 0 0 24 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 62 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _