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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAT2
All Species:
28.48
Human Site:
T412
Identified Species:
52.22
UniProt:
Q9NYQ8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYQ8
NP_001438.1
4349
479392
T412
G
F
K
L
N
A
R
T
G
L
I
T
T
T
K
Chimpanzee
Pan troglodytes
XP_001168406
4349
479255
T412
G
F
K
L
N
A
R
T
G
L
I
T
T
T
K
Rhesus Macaque
Macaca mulatta
XP_001110265
4349
479328
T412
G
F
K
L
N
A
R
T
G
L
I
T
T
T
K
Dog
Lupus familis
XP_536461
4354
480494
T415
G
F
R
L
N
A
R
T
G
L
M
T
T
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNA6
4555
501992
S425
Y
F
K
I
N
P
R
S
G
L
I
V
T
A
Q
Rat
Rattus norvegicus
O88277
4351
480635
T412
A
F
K
L
N
A
R
T
G
L
I
T
T
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508966
4273
469286
K437
E
P
A
V
G
S
D
K
F
T
V
V
S
V
R
Chicken
Gallus gallus
XP_414584
4382
482412
T415
H
F
K
I
N
P
H
T
G
L
I
T
T
V
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920058
4342
480159
T414
K
F
K
I
S
A
K
T
G
V
I
V
T
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW71
4705
524557
Q459
G
M
L
Y
T
A
K
Q
L
D
A
E
K
K
S
Honey Bee
Apis mellifera
XP_394631
3607
400577
Nematode Worm
Caenorhab. elegans
Q19319
4292
477180
I418
N
P
D
D
V
S
L
I
R
Y
S
L
E
Y
S
Sea Urchin
Strong. purpuratus
XP_785422
3852
424350
A90
T
D
L
A
V
S
G
A
R
H
F
A
S
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.2
88.3
N.A.
41
81.7
N.A.
64.6
62.2
N.A.
46.8
N.A.
31.9
20.6
26.1
20.4
Protein Similarity:
100
99.5
98.5
93.7
N.A.
59.4
90
N.A.
77.1
76.2
N.A.
64.6
N.A.
50.1
37.8
46.1
37.7
P-Site Identity:
100
100
100
86.6
N.A.
53.3
93.3
N.A.
0
60
N.A.
46.6
N.A.
13.3
0
0
0
P-Site Similarity:
100
100
100
100
N.A.
73.3
93.3
N.A.
33.3
73.3
N.A.
86.6
N.A.
20
0
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
54
0
8
0
0
8
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
8
0
0
8
0
0
8
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% E
% Phe:
0
62
0
0
0
0
0
0
8
0
8
0
0
0
0
% F
% Gly:
39
0
0
0
8
0
8
0
62
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
24
0
0
0
8
0
0
54
0
0
0
0
% I
% Lys:
8
0
54
0
0
0
16
8
0
0
0
0
8
16
39
% K
% Leu:
0
0
16
39
0
0
8
0
8
54
0
8
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
0
0
0
54
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
16
0
0
0
16
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
16
% Q
% Arg:
0
0
8
0
0
0
47
0
16
0
0
0
0
0
24
% R
% Ser:
0
0
0
0
8
24
0
8
0
0
8
0
16
8
16
% S
% Thr:
8
0
0
0
8
0
0
54
0
8
0
47
62
39
0
% T
% Val:
0
0
0
8
16
0
0
0
0
8
8
24
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
0
0
0
0
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _