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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAT2 All Species: 22.73
Human Site: Y395 Identified Species: 41.67
UniProt: Q9NYQ8 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYQ8 NP_001438.1 4349 479392 Y395 P A F P N L Q Y V L K P S S E
Chimpanzee Pan troglodytes XP_001168406 4349 479255 Y395 P A F P N L Q Y V L K P S S E
Rhesus Macaque Macaca mulatta XP_001110265 4349 479328 Y395 P A F P N L Q Y V L K P S S E
Dog Lupus familis XP_536461 4354 480494 Y398 R A F P N L Q Y V L K P S S E
Cat Felis silvestris
Mouse Mus musculus Q8BNA6 4555 501992 Y408 P E P L D V E Y K L L P G K D
Rat Rattus norvegicus O88277 4351 480635 Y395 T A L P N L R Y S L K P S S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508966 4273 469286 G420 S A V D I V E G D P G K H F R
Chicken Gallus gallus XP_414584 4382 482412 Y398 P V L P N L K Y V L R P T P D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001920058 4342 480159 F397 L S L K N T T F S I Q E N P D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VW71 4705 524557 G442 E I V G G N E G D E F R I N P
Honey Bee Apis mellifera XP_394631 3607 400577
Nematode Worm Caenorhab. elegans Q19319 4292 477180 I401 E M A P I G R I L Y R M N V N
Sea Urchin Strong. purpuratus XP_785422 3852 424350 P73 I A G V Y D K P D F I M A F H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.2 88.3 N.A. 41 81.7 N.A. 64.6 62.2 N.A. 46.8 N.A. 31.9 20.6 26.1 20.4
Protein Similarity: 100 99.5 98.5 93.7 N.A. 59.4 90 N.A. 77.1 76.2 N.A. 64.6 N.A. 50.1 37.8 46.1 37.7
P-Site Identity: 100 100 100 93.3 N.A. 26.6 66.6 N.A. 6.6 53.3 N.A. 6.6 N.A. 0 0 6.6 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 53.3 73.3 N.A. 20 80 N.A. 46.6 N.A. 13.3 0 33.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 54 8 0 0 0 0 0 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 8 8 0 0 24 0 0 0 0 0 24 % D
% Glu: 16 8 0 0 0 0 24 0 0 8 0 8 0 0 31 % E
% Phe: 0 0 31 0 0 0 0 8 0 8 8 0 0 16 0 % F
% Gly: 0 0 8 8 8 8 0 16 0 0 8 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % H
% Ile: 8 8 0 0 16 0 0 8 0 8 8 0 8 0 0 % I
% Lys: 0 0 0 8 0 0 16 0 8 0 39 8 0 8 0 % K
% Leu: 8 0 24 8 0 47 0 0 8 54 8 0 0 0 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 16 0 0 0 % M
% Asn: 0 0 0 0 54 8 0 0 0 0 0 0 16 8 8 % N
% Pro: 39 0 8 54 0 0 0 8 0 8 0 54 0 16 8 % P
% Gln: 0 0 0 0 0 0 31 0 0 0 8 0 0 0 0 % Q
% Arg: 8 0 0 0 0 0 16 0 0 0 16 8 0 0 16 % R
% Ser: 8 8 0 0 0 0 0 0 16 0 0 0 39 39 0 % S
% Thr: 8 0 0 0 0 8 8 0 0 0 0 0 8 0 0 % T
% Val: 0 8 16 8 0 16 0 0 39 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 54 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _