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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAT2
All Species:
23.94
Human Site:
Y4331
Identified Species:
43.89
UniProt:
Q9NYQ8
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYQ8
NP_001438.1
4349
479392
Y4331
Q
P
R
V
P
P
N
Y
E
G
S
D
M
V
E
Chimpanzee
Pan troglodytes
XP_001168406
4349
479255
Y4331
Q
P
R
V
P
P
N
Y
E
G
S
D
M
V
E
Rhesus Macaque
Macaca mulatta
XP_001110265
4349
479328
Y4331
Q
H
R
A
P
P
N
Y
E
G
S
D
M
V
E
Dog
Lupus familis
XP_536461
4354
480494
Y4336
Q
P
Q
A
P
P
N
Y
E
G
S
D
M
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNA6
4555
501992
F4521
E
M
S
A
R
C
G
F
D
D
S
E
V
A
M
Rat
Rattus norvegicus
O88277
4351
480635
Y4333
Q
P
R
A
P
P
N
Y
E
G
S
D
M
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508966
4273
469286
Y4255
Q
P
G
A
P
R
H
Y
E
G
S
D
M
V
E
Chicken
Gallus gallus
XP_414584
4382
482412
T4359
R
P
A
H
P
A
P
T
T
P
Q
L
X
G
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920058
4342
480159
Y4324
T
R
R
T
S
R
S
Y
A
G
S
D
R
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW71
4705
524557
D4571
D
I
A
A
L
N
E
D
I
G
S
E
Y
L
D
Honey Bee
Apis mellifera
XP_394631
3607
400577
K3590
E
Y
E
I
T
D
Q
K
S
N
G
R
L
W
L
Nematode Worm
Caenorhab. elegans
Q19319
4292
477180
A4267
G
E
E
A
P
R
N
A
L
Y
D
D
P
I
S
Sea Urchin
Strong. purpuratus
XP_785422
3852
424350
F3835
S
E
I
N
L
S
E
F
E
F
D
L
E
D
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.2
88.3
N.A.
41
81.7
N.A.
64.6
62.2
N.A.
46.8
N.A.
31.9
20.6
26.1
20.4
Protein Similarity:
100
99.5
98.5
93.7
N.A.
59.4
90
N.A.
77.1
76.2
N.A.
64.6
N.A.
50.1
37.8
46.1
37.7
P-Site Identity:
100
100
86.6
86.6
N.A.
6.6
93.3
N.A.
73.3
13.3
N.A.
46.6
N.A.
13.3
0
20
6.6
P-Site Similarity:
100
100
86.6
93.3
N.A.
40
93.3
N.A.
80
20
N.A.
53.3
N.A.
33.3
20
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
54
0
8
0
8
8
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
8
0
8
8
8
16
62
0
8
8
% D
% Glu:
16
16
16
0
0
0
16
0
54
0
0
16
8
0
54
% E
% Phe:
0
0
0
0
0
0
0
16
0
8
0
0
0
0
0
% F
% Gly:
8
0
8
0
0
0
8
0
0
62
8
0
0
8
0
% G
% His:
0
8
0
8
0
0
8
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
8
8
0
0
0
0
8
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
16
0
0
0
8
0
0
16
8
8
16
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
47
0
8
% M
% Asn:
0
0
0
8
0
8
47
0
0
8
0
0
0
0
0
% N
% Pro:
0
47
0
0
62
39
8
0
0
8
0
0
8
0
0
% P
% Gln:
47
0
8
0
0
0
8
0
0
0
8
0
0
0
0
% Q
% Arg:
8
8
39
0
8
24
0
0
0
0
0
8
8
0
0
% R
% Ser:
8
0
8
0
8
8
8
0
8
0
70
0
0
0
8
% S
% Thr:
8
0
0
8
8
0
0
8
8
0
0
0
0
0
0
% T
% Val:
0
0
0
16
0
0
0
0
0
0
0
0
8
54
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
8
0
0
0
0
0
54
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _