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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RDH8
All Species:
7.88
Human Site:
S247
Identified Species:
15.76
UniProt:
Q9NYR8
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYR8
NP_056540.1
311
33755
S247
Q
A
I
V
N
V
I
S
S
T
R
P
P
L
R
Chimpanzee
Pan troglodytes
Q1WNP0
328
34870
R246
E
V
F
L
T
A
L
R
A
P
K
P
T
L
R
Rhesus Macaque
Macaca mulatta
XP_001100028
311
33679
S247
Q
A
I
V
N
V
I
S
S
A
R
P
P
L
R
Dog
Lupus familis
XP_854042
312
34010
G248
Q
V
I
V
K
V
I
G
S
A
R
P
P
L
R
Cat
Felis silvestris
Mouse
Mus musculus
P51656
344
36767
T256
P
A
L
R
Y
F
S
T
N
R
F
L
P
L
A
Rat
Rattus norvegicus
P51657
344
36949
T256
P
A
L
R
Y
F
S
T
N
R
F
L
P
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506046
316
35562
V246
E
H
V
L
K
V
I
V
A
P
S
P
P
F
R
Chicken
Gallus gallus
XP_426642
317
35601
L246
E
H
T
V
K
I
I
L
A
E
N
P
P
F
R
Frog
Xenopus laevis
Q0IH28
323
35135
P253
N
T
A
D
G
R
T
P
E
E
V
A
Q
T
V
Zebra Danio
Brachydanio rerio
NP_957001
318
35407
E250
K
C
T
K
K
V
I
E
T
S
Q
P
R
F
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202510
216
23397
N157
L
P
Y
M
D
M
Y
N
A
S
K
F
A
M
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05016
267
29140
V208
V
E
T
E
F
S
L
V
R
Y
R
G
N
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.6
97.1
84.2
N.A.
37.7
38.3
N.A.
53.1
47.9
26.6
52.8
N.A.
N.A.
N.A.
N.A.
36.9
Protein Similarity:
100
55.7
98.7
91
N.A.
53.2
52.6
N.A.
71.8
68.4
45.5
74.2
N.A.
N.A.
N.A.
N.A.
50.4
P-Site Identity:
100
20
93.3
73.3
N.A.
20
20
N.A.
33.3
33.3
0
26.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
53.3
93.3
73.3
N.A.
40
40
N.A.
60
53.3
0
53.3
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
9
0
0
9
0
0
34
17
0
9
9
0
17
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
25
9
0
9
0
0
0
9
9
17
0
0
0
9
17
% E
% Phe:
0
0
9
0
9
17
0
0
0
0
17
9
0
25
0
% F
% Gly:
0
0
0
0
9
0
0
9
0
0
0
9
0
0
0
% G
% His:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
25
0
0
9
50
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
9
34
0
0
0
0
0
17
0
0
0
0
% K
% Leu:
9
0
17
17
0
0
17
9
0
0
0
17
0
50
0
% L
% Met:
0
0
0
9
0
9
0
0
0
0
0
0
0
9
0
% M
% Asn:
9
0
0
0
17
0
0
9
17
0
9
0
9
0
0
% N
% Pro:
17
9
0
0
0
0
0
9
0
17
0
59
59
0
0
% P
% Gln:
25
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% Q
% Arg:
0
0
0
17
0
9
0
9
9
17
34
0
9
0
59
% R
% Ser:
0
0
0
0
0
9
17
17
25
17
9
0
0
0
0
% S
% Thr:
0
9
25
0
9
0
9
17
9
9
0
0
9
9
0
% T
% Val:
9
17
9
34
0
42
0
17
0
0
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
17
0
9
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _