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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RDH8
All Species:
10.3
Human Site:
T269
Identified Species:
20.61
UniProt:
Q9NYR8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYR8
NP_056540.1
311
33755
T269
S
P
L
T
T
L
K
T
V
D
S
S
G
S
L
Chimpanzee
Pan troglodytes
Q1WNP0
328
34870
L268
L
P
L
L
R
M
R
L
D
D
P
S
G
S
N
Rhesus Macaque
Macaca mulatta
XP_001100028
311
33679
T269
S
P
L
T
M
L
K
T
V
D
S
S
G
S
L
Dog
Lupus familis
XP_854042
312
34010
A270
T
P
L
A
A
L
K
A
V
D
P
S
G
S
L
Cat
Felis silvestris
Mouse
Mus musculus
P51656
344
36767
A278
S
G
S
S
Y
V
A
A
M
H
Q
E
A
F
S
Rat
Rattus norvegicus
P51657
344
36949
A278
S
G
S
S
Y
V
E
A
M
H
R
E
A
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506046
316
35562
H268
T
P
L
T
T
L
K
H
A
D
P
T
G
N
L
Chicken
Gallus gallus
XP_426642
317
35601
Y268
T
P
M
T
T
L
K
Y
A
D
P
N
G
D
L
Frog
Xenopus laevis
Q0IH28
323
35135
G275
R
K
E
L
L
V
A
G
L
V
P
T
L
A
V
Zebra Danio
Brachydanio rerio
NP_957001
318
35407
Y272
T
P
I
V
A
M
K
Y
A
D
E
T
G
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202510
216
23397
I179
P
Q
L
K
N
F
G
I
S
I
S
T
V
Q
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05016
267
29140
D230
D
T
T
P
L
M
A
D
D
V
A
D
L
I
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.6
97.1
84.2
N.A.
37.7
38.3
N.A.
53.1
47.9
26.6
52.8
N.A.
N.A.
N.A.
N.A.
36.9
Protein Similarity:
100
55.7
98.7
91
N.A.
53.2
52.6
N.A.
71.8
68.4
45.5
74.2
N.A.
N.A.
N.A.
N.A.
50.4
P-Site Identity:
100
40
93.3
66.6
N.A.
6.6
6.6
N.A.
60
53.3
0
33.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
53.3
93.3
73.3
N.A.
26.6
33.3
N.A.
80
73.3
33.3
60
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
17
0
25
25
25
0
9
0
17
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
9
17
59
0
9
0
9
0
% D
% Glu:
0
0
9
0
0
0
9
0
0
0
9
17
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
17
0
% F
% Gly:
0
17
0
0
0
0
9
9
0
0
0
0
59
9
0
% G
% His:
0
0
0
0
0
0
0
9
0
17
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
9
0
9
0
0
0
9
0
% I
% Lys:
0
9
0
9
0
0
50
0
0
0
0
0
0
0
0
% K
% Leu:
9
0
50
17
17
42
0
9
9
0
0
0
17
0
50
% L
% Met:
0
0
9
0
9
25
0
0
17
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
0
9
0
9
9
% N
% Pro:
9
59
0
9
0
0
0
0
0
0
42
0
0
0
9
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
9
0
0
9
0
% Q
% Arg:
9
0
0
0
9
0
9
0
0
0
9
0
0
0
0
% R
% Ser:
34
0
17
17
0
0
0
0
9
0
25
34
0
34
17
% S
% Thr:
34
9
9
34
25
0
0
17
0
0
0
34
0
0
0
% T
% Val:
0
0
0
9
0
25
0
0
25
17
0
0
9
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
17
0
0
17
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _