KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RDH8
All Species:
19.39
Human Site:
Y220
Identified Species:
38.79
UniProt:
Q9NYR8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYR8
NP_056540.1
311
33755
Y220
L
H
Y
F
R
D
L
Y
L
P
A
S
R
K
L
Chimpanzee
Pan troglodytes
Q1WNP0
328
34870
A221
H
R
F
Y
Q
Y
L
A
H
S
K
Q
V
F
R
Rhesus Macaque
Macaca mulatta
XP_001100028
311
33679
Y220
L
H
Y
F
R
D
L
Y
L
P
A
S
R
E
L
Dog
Lupus familis
XP_854042
312
34010
Y221
L
H
Y
F
R
D
I
Y
L
P
A
S
R
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P51656
344
36767
R221
H
L
F
A
H
Y
L
R
G
Y
E
Q
A
L
S
Rat
Rattus norvegicus
P51657
344
36949
R221
H
L
F
A
H
Y
Q
R
G
Y
E
Q
A
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506046
316
35562
Y219
L
Q
I
F
Q
G
F
Y
M
T
Y
S
K
E
V
Chicken
Gallus gallus
XP_426642
317
35601
Y219
A
D
M
F
T
N
I
Y
L
K
N
Y
K
Q
I
Frog
Xenopus laevis
Q0IH28
323
35135
T217
S
P
Y
D
I
D
V
T
V
V
N
P
G
Y
I
Zebra Danio
Brachydanio rerio
NP_957001
318
35407
Y223
V
R
Y
F
K
D
V
Y
V
P
S
S
I
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202510
216
23397
K132
A
A
L
P
I
M
K
K
Q
K
S
G
R
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05016
267
29140
R183
G
A
F
T
D
S
L
R
K
E
L
I
N
T
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.6
97.1
84.2
N.A.
37.7
38.3
N.A.
53.1
47.9
26.6
52.8
N.A.
N.A.
N.A.
N.A.
36.9
Protein Similarity:
100
55.7
98.7
91
N.A.
53.2
52.6
N.A.
71.8
68.4
45.5
74.2
N.A.
N.A.
N.A.
N.A.
50.4
P-Site Identity:
100
6.6
93.3
86.6
N.A.
6.6
0
N.A.
26.6
20
13.3
40
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
26.6
100
100
N.A.
13.3
6.6
N.A.
60
53.3
33.3
80
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
17
0
17
0
0
0
9
0
0
25
0
17
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
9
9
42
0
0
0
0
0
0
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
17
0
0
25
0
% E
% Phe:
0
0
34
50
0
0
9
0
0
0
0
0
0
9
0
% F
% Gly:
9
0
0
0
0
9
0
0
17
0
0
9
9
0
0
% G
% His:
25
25
0
0
17
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
17
0
17
0
0
0
0
9
9
9
25
% I
% Lys:
0
0
0
0
9
0
9
9
9
17
9
0
17
9
9
% K
% Leu:
34
17
9
0
0
0
42
0
34
0
9
0
0
17
25
% L
% Met:
0
0
9
0
0
9
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
17
0
9
0
0
% N
% Pro:
0
9
0
9
0
0
0
0
0
34
0
9
0
0
0
% P
% Gln:
0
9
0
0
17
0
9
0
9
0
0
25
0
9
0
% Q
% Arg:
0
17
0
0
25
0
0
25
0
0
0
0
34
0
9
% R
% Ser:
9
0
0
0
0
9
0
0
0
9
17
42
0
0
17
% S
% Thr:
0
0
0
9
9
0
0
9
0
9
0
0
0
9
0
% T
% Val:
9
0
0
0
0
0
17
0
17
9
0
0
9
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
42
9
0
25
0
50
0
17
9
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _