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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKIRAS2
All Species:
24.24
Human Site:
S186
Identified Species:
38.08
UniProt:
Q9NYR9
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYR9
NP_001001349.1
191
21508
S186
L
S
R
K
N
K
G
S
G
S
L
D
G
_
_
Chimpanzee
Pan troglodytes
XP_511498
329
36197
S324
L
S
R
K
N
K
G
S
G
S
L
D
G
_
_
Rhesus Macaque
Macaca mulatta
XP_001093984
331
35945
S326
L
S
R
K
N
K
G
S
G
S
L
D
G
_
_
Dog
Lupus familis
XP_534244
192
21653
G186
L
P
G
R
K
N
K
G
N
S
S
S
E
N
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR56
191
21476
S186
L
S
R
K
N
K
G
S
G
S
L
D
G
_
_
Rat
Rattus norvegicus
P63033
266
30178
Y208
H
H
K
I
S
V
Q
Y
G
D
A
F
H
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508842
191
21601
S186
L
S
R
K
N
K
G
S
G
S
T
D
A
_
_
Chicken
Gallus gallus
Q5ZJW6
191
21484
S186
L
S
R
K
N
K
G
S
G
S
V
D
G
_
_
Frog
Xenopus laevis
Q32NS2
163
18379
Zebra Danio
Brachydanio rerio
Q6DGL2
192
21894
T186
L
S
R
N
K
N
K
T
S
G
S
L
D
S
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4L4
201
22789
N195
Q
L
R
Q
V
M
Q
N
R
Q
K
S
E
A
_
Honey Bee
Apis mellifera
XP_395111
201
22615
N195
Q
L
S
M
G
R
K
N
I
K
I
E
G
P
_
Nematode Worm
Caenorhab. elegans
Q19143
199
22551
E188
L
S
K
K
L
K
S
E
K
S
S
N
P
A
I
Sea Urchin
Strong. purpuratus
XP_001202670
179
20160
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P16976
208
23293
V187
L
E
R
K
P
S
N
V
V
Q
M
K
G
R
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.5
53.4
70.8
N.A.
98.9
24.4
N.A.
90.5
92.6
63.8
78.1
N.A.
38.3
47.2
42.2
49.2
Protein Similarity:
100
56.5
57
83.8
N.A.
100
37.2
N.A.
96.8
97.3
75.3
87.5
N.A.
56.2
64.6
55.7
64.9
P-Site Identity:
100
100
100
14.2
N.A.
100
6.6
N.A.
84.6
92.3
0
21.4
N.A.
7.1
7.1
33.3
0
P-Site Similarity:
100
100
100
21.4
N.A.
100
20
N.A.
84.6
100
0
28.5
N.A.
21.4
35.7
53.3
0
Percent
Protein Identity:
N.A.
25
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
44.7
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
7
0
7
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
7
0
40
7
0
0
% D
% Glu:
0
7
0
0
0
0
0
7
0
0
0
7
14
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% F
% Gly:
0
0
7
0
7
0
40
7
47
7
0
0
47
0
0
% G
% His:
7
7
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
7
0
7
0
0
0
7
% I
% Lys:
0
0
14
54
14
47
20
0
7
7
7
7
0
0
0
% K
% Leu:
67
14
0
0
7
0
0
0
0
0
27
7
0
0
0
% L
% Met:
0
0
0
7
0
7
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
7
40
14
7
14
7
0
0
7
0
7
0
% N
% Pro:
0
7
0
0
7
0
0
0
0
0
0
0
7
14
7
% P
% Gln:
14
0
0
7
0
0
14
0
0
14
0
0
0
0
0
% Q
% Arg:
0
0
60
7
0
7
0
0
7
0
0
0
0
7
7
% R
% Ser:
0
54
7
0
7
7
7
40
7
54
20
14
0
7
0
% S
% Thr:
0
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% T
% Val:
0
0
0
0
7
7
0
7
7
0
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
40
67
% _