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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NKIRAS2 All Species: 24.48
Human Site: S188 Identified Species: 38.46
UniProt: Q9NYR9 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYR9 NP_001001349.1 191 21508 S188 R K N K G S G S L D G _ _ _ _
Chimpanzee Pan troglodytes XP_511498 329 36197 S326 R K N K G S G S L D G _ _ _ _
Rhesus Macaque Macaca mulatta XP_001093984 331 35945 S328 R K N K G S G S L D G _ _ _ _
Dog Lupus familis XP_534244 192 21653 S188 G R K N K G N S S S E N _ _ _
Cat Felis silvestris
Mouse Mus musculus Q9CR56 191 21476 S188 R K N K G S G S L D G _ _ _ _
Rat Rattus norvegicus P63033 266 30178 D210 K I S V Q Y G D A F H P R P F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508842 191 21601 S188 R K N K G S G S T D A _ _ _ _
Chicken Gallus gallus Q5ZJW6 191 21484 S188 R K N K G S G S V D G _ _ _ _
Frog Xenopus laevis Q32NS2 163 18379
Zebra Danio Brachydanio rerio Q6DGL2 192 21894 G188 R N K N K T S G S L D S _ _ _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V4L4 201 22789 Q197 R Q V M Q N R Q K S E A _ _ _
Honey Bee Apis mellifera XP_395111 201 22615 K197 S M G R K N I K I E G P _ _ _
Nematode Worm Caenorhab. elegans Q19143 199 22551 S190 K K L K S E K S S N P A I L M
Sea Urchin Strong. purpuratus XP_001202670 179 20160
Poplar Tree Populus trichocarpa
Maize Zea mays P16976 208 23293 Q189 R K P S N V V Q M K G R P I Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.5 53.4 70.8 N.A. 98.9 24.4 N.A. 90.5 92.6 63.8 78.1 N.A. 38.3 47.2 42.2 49.2
Protein Similarity: 100 56.5 57 83.8 N.A. 100 37.2 N.A. 96.8 97.3 75.3 87.5 N.A. 56.2 64.6 55.7 64.9
P-Site Identity: 100 100 100 8.3 N.A. 100 6.6 N.A. 81.8 90.9 0 8.3 N.A. 8.3 8.3 20 0
P-Site Similarity: 100 100 100 16.6 N.A. 100 20 N.A. 81.8 100 0 16.6 N.A. 25 41.6 40 0
Percent
Protein Identity: N.A. 25 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 44.7 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 20 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 33.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 7 0 7 14 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 7 0 40 7 0 0 0 0 % D
% Glu: 0 0 0 0 0 7 0 0 0 7 14 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % F
% Gly: 7 0 7 0 40 7 47 7 0 0 47 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 7 0 7 0 0 0 7 7 0 % I
% Lys: 14 54 14 47 20 0 7 7 7 7 0 0 0 0 0 % K
% Leu: 0 0 7 0 0 0 0 0 27 7 0 0 0 7 0 % L
% Met: 0 7 0 7 0 0 0 0 7 0 0 0 0 0 7 % M
% Asn: 0 7 40 14 7 14 7 0 0 7 0 7 0 0 0 % N
% Pro: 0 0 7 0 0 0 0 0 0 0 7 14 7 7 0 % P
% Gln: 0 7 0 0 14 0 0 14 0 0 0 0 0 0 7 % Q
% Arg: 60 7 0 7 0 0 7 0 0 0 0 7 7 0 0 % R
% Ser: 7 0 7 7 7 40 7 54 20 14 0 7 0 0 0 % S
% Thr: 0 0 0 0 0 7 0 0 7 0 0 0 0 0 0 % T
% Val: 0 0 7 7 0 7 7 0 7 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 40 67 67 67 % _